SCHEMBL30466124

SCHEMBL30466124

CSCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@H](CCSC)C(N)=O)C(C)C

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 7/20 0.61
▸ NPY1R P25929 3/20 0.58
▸ NPY2R P49146 3/20 0.58
▸ NPY4R P50391 3/20 0.58
▸ KISS1R Q969F8 1/20 0.57
▸ IL23R Q5VWK5 1/20 0.55
▸ UTS2R Q9UKP6 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3486221 1.00 GHSR (0.61) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL29434320 1.00 GHSR (0.61) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL3486226 1.00 GHSR (0.61) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL29388140 0.94 GHSR (0.55) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL29534023 0.94 GHSR (0.55) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL14509563 0.91 GHSR (0.65) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL31404052 0.90 GHSR (0.68) GHSRNPY1RNPY2RNPY4RKISS1R
SCHEMBL21185972 0.90 IL23R (0.65) KISS1RIL23R
SCHEMBL16358972 0.88 GHSR (0.61) GHSRUTS2R
SCHEMBL30053610 0.88 GHSR (0.71) GHSRNPY1RNPY2RNPY4RUTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207212-A1 METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION UNIVERSITY OF MASSACHUSETTS 2024-06-27 — — US disclosed
US-11865093-B2 Methods and compositions for treating inflammation UNIVERSITY OF MASSACHUSETTS (US) 2024-01-09 — — US disclosed
US-11707486-B2 Natural killer cell expressing anti-cotinine chimeric antigen receptor KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2023-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11707486-B2 Natural killer cell expressing anti-cotinine chimeric antigen receptor PBK, KLK3, KLRK1 GHSR 1697/4885NPY1R 3679/4885NPY2R 3693/4885
US-11865093-B2 Methods and compositions for treating inflammation ABCC3, ABCC1, ABCE1 GHSR 3386/4885NPY1R 2917/4885NPY2R 2548/4885
US-20240207212-A1 METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION ABCC3, ABCC1, ABCE1 GHSR 3386/4885NPY1R 2917/4885NPY2R 2548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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