Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488823 | 0.84 | ADORA2A (0.51) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3488590 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6696026 | 0.77 | KMT2A (0.67) | KDM4EALDH1A1MAPTFABP4FABP5 | |
| SCHEMBL18916875 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL3486575 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL12014939 | 0.76 | KDM4E (0.68) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL6696024 | 0.75 | MAPT (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2FABP4 | |
| SCHEMBL19850765 | 0.73 | PTGFR (0.52) | KDM4EALDH1A1LMNAMAPTFABP4 | |
| SCHEMBL19639039 | 0.72 | KDM4E (0.71) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL17367223 | 0.72 | KDM4E (0.71) | KDM4EALDH1A1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096025-B2 | Silicone hydrogel lenses with convertible comfort agents | NOVARTIS AG (CH) | 2015-08-04 | — | — | US | disclosed |
| EP-2100507-B1 | QUINAZOLINE DERIVATIVES CAPABLE OF INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-8722580-B2 | Agent for inhibiting cytokinin signaling | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20130127077-A1 | SILICONE HYDROGEL LENSES WITH CONVERTIBLE COMFORT AGENTS | NOVARTIS AG (CH) | 2013-05-23 | — | — | US | disclosed |
| US-8357760-B2 | Silicone hydrogel contact lenses with convertible comfort agents | NOVARTIS AG (CH) | 2013-01-22 | — | — | US | disclosed |
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20100016514-A1 | Silicone Hydrogel Contact Lenses with Convertible Comfort Agents | ALCON INC. (CH) | 2010-01-21 | — | — | US | disclosed |
| EP-2100507-A1 | SUBSTANCE CAPABLE OF INHIBITING CYTOKININ SIGNALING | Sumitomo Chemical Company, Limited (JP) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | CROCC, STAT3, GRK6 | KDM4E 4572/4885ALDH1A1 2316/4885LMNA 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.