SCHEMBL17367223

SCHEMBL17367223

Clc1nc(-c2ccccc2)c2cc(-c3ccccc3)ccc2n1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.71
ALDH1A1 P00352 5/20 0.71
LMNA P02545 4/20 0.71
MAPT P10636 4/20 0.71
KMT2A Q03164 3/20 0.61
OPRK1 P41145 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.53
HPGD P15428 2/20 0.53
GLA P06280 1/20 0.53
GAA P10253 2/20 0.49
MAT2A P31153 1/20 0.49
MAPK1 P28482 1/20 0.47
TP53 P04637 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.46
MEN1 O00255 1/20 0.46
PIK3CD O00329 1/20 0.46
PIK3CA P42336 1/20 0.46
PIK3CB P42338 1/20 0.46
MTOR P42345 1/20 0.46
PIK3CG P48736 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19639039 1.00 KDM4E (0.71) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL29992999 1.00 KDM4E (0.71) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL19961762 0.89 KDM4E (0.57) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL21174624 0.88 KDM4E (0.57) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL18916876 0.88 KDM4E (0.61) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL17299607 0.86 KDM4E (0.69) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL3486575 0.86 KDM4E (0.71) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL17286874 0.85 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL808191 0.85 KDM4E (0.77) KDM4EALDH1A1LMNAMAPTKMT2A
SCHEMBL8899763 0.84 KDM4E (0.50) KDM4EALDH1A1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185324-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-10-04 EP disclosed
CN-110770225-B Compound and organic electroluminescent device comprising same 株式会社LG化学 2022-10-11 CN disclosed
EP-3244465-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-04-20 EP disclosed
EP-3176845-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-03-16 EP disclosed
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-11217754-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2022-01-04 US disclosed
EP-3389106-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-12-01 EP disclosed
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2021-10-21 US disclosed
WO-2021112478-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-06-10 WO disclosed
US-10840457-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2020-11-17 US disclosed
EP-3244465-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
US-20170271599-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-09-21 US disclosed
CN-107078224-A Organic electroluminescence device 保土谷化学工业株式会社 2017-08-18 CN disclosed
WO-2017135717-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2017-08-10 WO disclosed
EP-3185324-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-06-28 EP disclosed
EP-3176845-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-06-07 EP disclosed
CN-106796993-A Organic electroluminescence device 保土谷化学工业株式会社 2017-05-31 CN disclosed
WO-2017052099-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2017-03-30 WO disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170271599-A1 ORGANIC ELECTROLUMINESCENT DEVICE AHR, SLC43A1, KCNN4 KDM4E 2048/4885ALDH1A1 185/4885LMNA 844/4885
US-10840457-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof PIEZO1, OR10J3, OCIAD1 KDM4E 930/4885ALDH1A1 572/4885LMNA 2161/4885
US-20210328153-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES IDO1, IDO2, AZI2 KDM4E 156/4885ALDH1A1 1455/4885LMNA 1885/4885
US-11217754-B2 Organic electroluminescence device TYR, SLC18A1, SLC18A3 KDM4E 1504/4885ALDH1A1 843/4885LMNA 2962/4885
US-20150380663-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CYP1A1, CRY1, CYP1B1 KDM4E 3404/4885ALDH1A1 13/4885LMNA 1789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.