Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15387515 | 0.90 | MME (0.55) | MMEALDH1A1MAPTHPGD | |
| SCHEMBL9633609 | 0.90 | MME (0.55) | MMEALDH1A1MAPTHPGD | |
| SCHEMBL15387514 | 0.90 | MME (0.55) | MMEALDH1A1MAPTHPGD | |
| SCHEMBL15156774 | 0.83 | MME (0.45) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL15156784 | 0.83 | MME (0.45) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL3487775 | 0.83 | MME (0.45) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL3488160 | 0.83 | MME (0.45) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL9654344 | 0.81 | MEP1B (0.50) | MME | |
| SCHEMBL9657153 | 0.81 | MEP1B (0.50) | MME | |
| SCHEMBL31074731 | 0.78 | OPRD1 (0.49) | MMEACECPA1ACE2CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835132-B2 | Method for making acylated polypeptides | NOVO NORDISK A/S (DK) | 2014-09-16 | — | — | US | disclosed |
| EP-2084270-B1 | PRODUCTION OF BETA-LACTAM ANTIBIOTICS | DSM SINOCHEM PHARM NL BV (NL) | 2013-11-20 | — | — | EP | disclosed |
| US-8293511-B2 | Production of β-Lactam antibiotics | DSM IP ASSETS B.V. (NL) | 2012-10-23 | — | — | US | disclosed |
| US-20100055738-A1 | Method for Making Acylated Polypeptides | NOVO NORDISK A/S (DK) | 2010-03-04 | — | — | US | disclosed |
| US-20100009404-A1 | PRODUCTION OF BETA-LACTAM ANTIBIOTICS | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2010-01-14 | — | — | US | disclosed |
| US-7595172-B2 | Expressing a precursor polypeptide that has an n-terminal extension cleavable from the polypeptide at a lysine cleavage site, acylating and removing N-terminal extension by enzymatic cleavage | NOVO NORDISK A/S (DK) | 2009-09-29 | — | — | US | disclosed |
| EP-2084270-A2 | PRODUCTION OF BETA-LACTAM ANTIBIOTICS | DSMIP Assets B.V. (NL) | 2009-08-05 | — | — | EP | disclosed |
| EP-1421103-B1 | METHOD FOR MAKING ACYLATED POLYPEPTIDES | NOVO NORDISK AS (DK) | 2008-10-15 | — | — | EP | disclosed |
| WO-2008040731-A2 | PRODUCTION OF BETA-LACTAM ANTIBIOTICS | DSM IP ASSETS B.V. (NL) | 2008-04-10 | — | — | WO | disclosed |
| EP-1421103-A2 | METHOD FOR MAKING ACYLATED POLYPEPTIDES | NOVO NORDISK A/S (DK) | 2004-05-26 | — | — | EP | disclosed |
| US-20030144471-A1 | Expressing a precursor polypeptide that has an n-terminal extension cleavable from the polypeptide at a lysine cleavage site, acylating and removing N-terminal extension by enzymatic cleavage | NOVO NORDISK A/S (DK) | 2003-07-31 | — | — | US | disclosed |
| WO-2003010186-A2 | METHOD FOR MAKING ACYLATED POLYPEPTIDES | NOVO NORDISK A/S (DK) | 2003-02-06 | — | — | WO | disclosed |