SCHEMBL3486770

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3486324	0.91	RET (0.57)	RETCHEK1KDRPDPK1TLK2
	SCHEMBL3486051	0.91	RET (0.53)	RETCHEK1KDRPDPK1TLK2
	SCHEMBL4064004	0.81	ALK (0.55)	RETKDRPDGFRBFLT3ALK
	SCHEMBL5362637	0.77	TLK2 (0.77)	RETKDRPDPK1TLK2PDGFRB
	SCHEMBL13432277	0.73	RET (0.69)	RETKDRPDPK1TLK2PDGFRB
	SCHEMBL3953189	0.73	KDR (0.69)	RETCHEK1KDRPDPK1TLK2
	SCHEMBL5366277	0.72	RET (0.64)	RETCHEK1KDRPDPK1TLK2
	SCHEMBL14301681	0.72	RET (0.60)	RETKDRPDPK1TLK2PDGFRB
	SCHEMBL5470645	0.72	RET (0.60)	RETKDRPDPK1TLK2PDGFRB
	SCHEMBL5470642	0.72	RET (0.60)	RETKDRPDPK1TLK2PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.