Biphenyl

Biphenyl

SCHEMBL3486918

Oc1cccc2c1[nH]c1ccccc12.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.57
KIF11 P52732 4/20 0.53
IMPDH2 P12268 1/20 0.53
IMPDH1 P20839 1/20 0.53
HTR2B P41595 1/20 0.53
HTR5A P47898 1/20 0.53
TDO2 P48775 1/20 0.53
CDK4 P11802 2/20 0.50
CCND1 P24385 2/20 0.50
APP P05067 1/20 0.49
ALDH1A1 P00352 1/20 0.48
GPR3 P46089 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MPL P40238 1/20 0.48
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
GABRA1 P14867 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
GABRB3 P28472 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329557 0.94 AR (0.62) ARKIF11IMPDH2IMPDH1TDO2
SCHEMBL28463756 0.92 AR (0.61) ARKIF11IMPDH2IMPDH1TDO2
SCHEMBL10868611 0.92 AR (0.61) ARKIF11IMPDH2IMPDH1TDO2
SCHEMBL28467939 0.92 AR (0.61) ARKIF11IMPDH2IMPDH1TDO2
Acetic Acid SCHEMBL27471236 0.87 PARP14 (0.56) ARKIF11IMPDH2IMPDH1APP
SCHEMBL28911952 0.82 AR (0.51) ARKIF11IMPDH2IMPDH1HTR2B
SCHEMBL29001969 0.80 ESR1 (0.50) KIF11HTR2BHTR5ATDO2APP
SCHEMBL15455181 0.79 PARP14 (0.59) KIF11IMPDH2IMPDH1CDK4CCND1
SCHEMBL30600352 0.79 PARP14 (0.59) KIF11IMPDH2IMPDH1CDK4CCND1
SCHEMBL4010925 0.79 TDP1 (0.64) ARIMPDH2IMPDH1ALDH1A1CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7651790-B2 bipolar phosphorescent host containing 4,4'-biscarbazolylbiphenyl hole transport unit attached to electron transport unit selected from fluorene or spirofluorene and an aluminum hydroquinoline unit; phospherescent dopant e.g. tris(3-biphenylpyridine)Iridium; high efficiency and a long lifetime SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-01-26 US disclosed
US-20060263631-A1 bipolar phosphorescent host containing 4,4'-biscarbazolylbiphenyl hole transport unit attached to electron transport unit selected from fluorene or spirofluorene and an aluminum hydroquinoline unit; phospherescent dopant e.g. tris(3-biphenylpyridine)Iridium; high efficiency and a long lifetime SAMSUNG SDI CO., LTD. 2006-11-23 US disclosed