Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.52 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329557 | 0.84 | AR (0.62) | KDM4EALDH1A1HTTHPGDMEN1 | |
| SCHEMBL28463756 | 0.82 | AR (0.61) | KDM4EALDH1A1HTTHPGDMEN1 | |
| SCHEMBL10868611 | 0.82 | AR (0.61) | KDM4EALDH1A1HTTHPGDMEN1 | |
| SCHEMBL28467939 | 0.82 | AR (0.61) | KDM4EALDH1A1HTTHPGDMEN1 | |
| Biphenyl SCHEMBL3486918 | 0.79 | AR (0.57) | ALDH1A1CHEK1IMPDH2IMPDH1AR | |
| Acetic Acid SCHEMBL27471236 | 0.79 | PARP14 (0.56) | TDP1PBRM1KDM4EHTTIMPDH2 | |
| SCHEMBL13019547 | 0.79 | GAA (0.57) | TDP1POLBPBRM1KDM4EALDH1A1 | |
| SCHEMBL14552258 | 0.79 | ALDH1A1 (0.68) | TDP1POLBPBRM1KDM4EALDH1A1 | |
| SCHEMBL9348524 | 0.78 | IMPDH2 (0.72) | TDP1POLBPBRM1KDM4EALDH1A1 | |
| SCHEMBL25246575 | 0.78 | POLB (0.64) | TDP1POLBPBRM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118726991-A | Low-corrosion aluminum programming chip cleaning liquid and preparation method and application thereof | 浙江奥首材料科技有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-118726991-A | Low-corrosion aluminum programming chip cleaning liquid and preparation method and application thereof | 浙江奥首材料科技有限公司 | 2024-10-01 | — | — | CN | disclosed |
| US-20110105554-A1 | MEANS FOR TREATING MYOSIN-RELATED DISEASES | KINARIS BIOMEDICALS GMBH (DE) | 2011-05-05 | — | — | US | disclosed |
| US-7485649-B2 | Inhibitors of checkpoint kinases | MERCK & CO., INC. (US) | 2009-02-03 | — | — | US | disclosed |
| US-20080214594-A1 | Inhibitors Of Checkpoint Kinases | MERCK SHARP & DOHME CORP. | 2008-09-04 | — | — | US | disclosed |
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
| EP-1836807-A2 | INHIBITORS OF CHECKPOINT KINASES | Merck & Co., Inc. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006074207-A2 | INHIBITORS OF CHECKPOINT KINASES | MERCK & CO., INC. (US) | 2006-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214594-A1 | Inhibitors Of Checkpoint Kinases | CHEK1, CHEK2, BUB1B | TDP1 601/4885POLB 679/4885PBRM1 888/4885 |
| US-20110105554-A1 | MEANS FOR TREATING MYOSIN-RELATED DISEASES | MYH14, MYH2, MYLK2 | TDP1 441/4885POLB 1191/4885PBRM1 4700/4885 |
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | BCL9, MCL1, BCL9L | TDP1 223/4885POLB 178/4885PBRM1 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.