Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980203 | 0.84 | TNKS (0.66) | TNKSCSNK2A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7618483 | 0.83 | KDM4E (0.46) | RAB9ANPC1KDM4EALDH1A1KMT2A | |
| SCHEMBL7618637 | 0.81 | RARA (0.50) | TNKSRAB9ANPC1MAOBMAOA | |
| SCHEMBL7624863 | 0.80 | MAOB (0.51) | RAB9ANPC1MEN1KMT2AMAOB | |
| SCHEMBL7625464 | 0.80 | RARA (0.44) | RAB9ANPC1RARARARBRARG | |
| SCHEMBL7625527 | 0.80 | TNKS (0.48) | TNKSRAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL7618545 | 0.80 | TNKS (0.48) | TNKSRARARARBRARGNQO2 | |
| SCHEMBL7628810 | 0.78 | RARA (0.54) | KDM4EALDH1A1KMT2AMAPTRARA | |
| SCHEMBL7725462 | 0.78 | RARA (0.41) | TNKSKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL7618653 | 0.78 | RARA (0.42) | RAB9ANPC1TP53MAPTRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063162-A1 | METHOD FOR PREDICTING EFFICACY OF RAR-ALPHA AGONIST | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-11 | — | — | US | disclosed |
| EP-1950293-A1 | METHOD FOR PREDICTION OF EFFECTIVENESS OF RAR- AGONIST | Taiho Pharmaceutical Co., Ltd. (JP) | 2008-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063162-A1 | METHOD FOR PREDICTING EFFICACY OF RAR-ALPHA AGONIST | RARA, RARB, RARG | KDM5A 3610/4885KDM4C 4295/4885KDM5B 4160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.