Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10010582 | 0.89 | LMNA (0.38) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL27878788 | 0.86 | LMNA (0.61) | ALDH1A1LMNAMAPTMAPK1MEN1 | |
| SCHEMBL9100884 | 0.85 | LMNA (0.48) | ALDH1A1LMNAMAPTMAPK1MEN1 | |
| SCHEMBL10009455 | 0.85 | LMNA (0.44) | ALDH1A1LMNAMAPTMAPK1MEN1 | |
| SCHEMBL10010733 | 0.82 | LMNA (0.33) | LMNAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10012234 | 0.82 | EGLN1 (0.41) | LMNAMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10012442 | 0.82 | LMNA (0.33) | LMNAMEN1KMT2ATDP1 | |
| SCHEMBL10011858 | 0.82 | TSHR (0.52) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL7287991 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTMAPK1CES2 | |
| SCHEMBL28387385 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187737-B2 | Mutants of a pseudomonas glumae butynol esterase | BASF SE (DE) | 2015-11-17 | — | — | US | disclosed |
| CN-104795595-A | Nonaqueous electrolyte solution and electrochemical element using same | UBE INDUSTRIES | 2015-07-22 | — | — | CN | disclosed |
| CN-102498605-B | Nonaqueous electrolyte solution and electrochemical element using same | UBE INDUSTRIES | 2015-05-20 | — | — | CN | disclosed |
| CN-101501189-B | Proteins with esterase activity | BASF SE | 2012-09-26 | — | — | CN | disclosed |
| US-20100196970-A1 | Butynol I esterase | HAUER BERNHARD | 2010-08-05 | — | — | US | disclosed |
| US-20100068760-A1 | PROTEINS WITH ESTERASE ACTIVITY | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| EP-1169467-B1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | CHIROTECH TECHNOLOGY LTD (GB) | 2010-02-17 | — | — | EP | disclosed |
| CN-101501189-A | Proteins with esterase activity | BASF SE (DE) | 2009-08-05 | — | — | CN | disclosed |
| US-7531331-B2 | Butynol I esterase | BASF AKTIENGESELLSCHAFT (DE) | 2009-05-12 | — | — | US | disclosed |
| CN-100379867-C | Butinol I esterase | BASF AG (DE) | 2008-04-09 | — | — | CN | disclosed |
| US-7314739-B2 | Lipase variants | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-01 | — | — | US | disclosed |
| US-20050255571-A1 | Biocatalysts in chemical reactions, activity, stability and enantioselectivity; for the preparation of optically active compounds | BASF AKTIENGESELLSCHAFT (DE) | 2005-11-17 | — | — | US | disclosed |
| US-20050181472-A1 | Butinol i esterase | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | US | disclosed |
| CN-1449447-A | Butinol I esterase | BASF AG (DE) | 2003-10-15 | — | — | CN | disclosed |
| US-6596520-B1 | Preparation of immobilized lipase; obtain crude lipase solution, expose to polypropylene, adsorb lipase to polypropylene particles, recover immbolized lipase | BASF AKTIENGESELLSCHAFT (DE) | 2003-07-22 | — | — | US | disclosed |