Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.49 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860404 | 0.89 | KIF11 (0.56) | KDM4EHSD17B10MEN1KMT2ACASP1 | |
| SCHEMBL11603400 | 0.81 | KDM4E (0.69) | KDM4EHSD17B10MEN1KMT2ACASP1 | |
| SCHEMBL17367218 | 0.81 | KDM4E (0.73) | KDM4EHSD17B10MEN1KMT2ACASP1 | |
| SCHEMBL11604874 | 0.78 | KDM4E (0.69) | KDM4EHSD17B10MEN1KMT2ACASP1 | |
| SCHEMBL6871615 | 0.78 | KDM4E (1.00) | KDM4EHSD17B10MEN1KMT2ACASP1 | |
| SCHEMBL11605848 | 0.78 | KDM4E (0.69) | KDM4EHSD17B10MEN1KMT2ACASP1 | |
| SCHEMBL5377653 | 0.78 | MAP2K4 (0.73) | KDM4EALDH1A1HPGDKIF11MAP2K4 | |
| SCHEMBL4142958 | 0.77 | KDM4E (1.00) | KDM4EHSD17B10MEN1KMT2ACASP1 | |
| Lithium SCHEMBL30669498 | 0.76 | KDM4E (0.96) | KDM4EHSD17B10MEN1KMT2ACASP1 | |
| SCHEMBL11459542 | 0.75 | PDE3B (0.69) | KDM4EHSD17B10MEN1KMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100507-B1 | QUINAZOLINE DERIVATIVES CAPABLE OF INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-8722580-B2 | Agent for inhibiting cytokinin signaling | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-13 | — | — | US | disclosed |
| CN-101588716-B | Substance capable of inhibiting cytokinin signaling | SUMITOMO CHEMICAL CO | 2014-03-05 | — | — | CN | disclosed |
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| CN-101588716-A | Substance capable of inhibiting cytokinin signaling | SUMITOMO CHEMICAL CO (JP) | 2009-11-25 | — | — | CN | disclosed |
| EP-2100507-A1 | SUBSTANCE CAPABLE OF INHIBITING CYTOKININ SIGNALING | Sumitomo Chemical Company, Limited (JP) | 2009-09-16 | — | — | EP | disclosed |
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |
| US-4067868-A | Production of quinazolinone compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | CROCC, STAT3, GRK6 | KDM4E 4572/4885HSD17B10 4139/4885MEN1 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.