Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FASN | P49327 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.46 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543395 | 0.90 | MAPT (0.67) | MAPTHPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL3488154 | 0.89 | KDM4E (0.64) | KIF11HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL4132327 | 0.78 | KIF11 (0.86) | KIF11MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL27939168 | 0.76 | KIF11 (0.54) | KIF11MAPTHPGDKMT2AMEN1 | |
| SCHEMBL29130445 | 0.75 | KDM4E (0.68) | MAPTHPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL5378388 | 0.74 | MAPT (0.68) | KIF11MAPTHPGDKMT2AMEN1 | |
| SCHEMBL11013508 | 0.74 | NPBWR1 (0.55) | MAPTHPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL4127278 | 0.72 | KIF11 (1.00) | KIF11CTSVCTSLPARP1 | |
| SCHEMBL4136730 | 0.72 | KIF11 (0.89) | KIF11CTSVCTSLPARP1 | |
| SCHEMBL11603400 | 0.72 | KDM4E (0.69) | HPGDKDM4EHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953446-A | Process for preparing quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | disclosed |