Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.55 |
| ▸ | PDE4A | P27815 | 6/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 3/20 | 0.39 |
| ▸ | TPO | P07202 | 3/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20653044 | 0.87 | ADORA2A (0.58) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL150602 | 0.75 | ADORA2B (0.59) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| 3-Methylxanthine SCHEMBL237146 | 0.75 | ADORA2A (0.64) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6662593 | 0.75 | PNP (0.57) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6310571 | 0.74 | ADORA2A (0.70) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL295963 | 0.74 | ADORA2B (0.78) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| 3-Methylxanthine SCHEMBL30753411 | 0.73 | ADORA2A (0.62) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| 3-Methylxanthine SCHEMBL9317914 | 0.73 | ADORA2A (0.62) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| 3-Methylxanthine SCHEMBL4020124 | 0.73 | ADORA2A (0.62) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6458349 | 0.73 | PDE2A (0.38) | ADORA2AADORA2BADORA1HPGDPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10106797-B2 | Methods for suppressing adipocyte differentiation | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2018-10-23 | — | — | US | disclosed |
| US-20160160219-A1 | COMPOSITION CONTAINING PPAR-gamma NEDDYLATION INHIBITOR FOR INHIBITING ADIPOCYTE DIFFERENTIATION AND USE THEREOF | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2016-06-09 | — | — | US | disclosed |
| WO-2015009094-A1 | COMPOSITION CONTAINING PPAR-Ν NEDDYLATION INHIBITOR FOR INHIBITING ADIPOCYTE DIFFERENTIATION AND USE THEREOF | 서울대학교산학협력단 (KR) | 2015-01-22 | — | — | WO | disclosed |
| US-20100062038-A1 | Markers, Antibodies and Recombinant scFvs for Mesenchymal Stem Cell Sub-populations and Osteoclasts | NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) | 2010-03-11 | — | — | US | disclosed |
| EP-2118272-A2 | MARKERS, ANTIBODIES AND RECOMBINANT SCFVS FOR MESENCHYMAL STEM CELL-SUB-POPULATIONS AND OSTEOCLASTS | National University of Ireland, Galway (IE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008110578-A2 | MARKERS, ANTIBODIES AND RECOMBINANT SCFVS FOR MESENCHYMAL STEM CELL-SUB-POPULATIONS AND OSTEOCLASTS | NATIONAL UNIVERSITY OF IRELAND, GALWAY (IE) | 2008-09-18 | — | — | WO | disclosed |
| US-20060094013-A1 | Salt-inducible kinases 2 and use thereof | TAKEMORI, HIROSHI (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1468078-A1 | METHOD AND DEVICE FOR IDENTIFYING SUBSTANCES CAPABLE OF MODULATING ADIPOCYTE DIFFERENTIATION | Genfit (FR) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003060106-A1 | METHOD AND DEVICE FOR IDENTIFYING SUBSTANCES CAPABLE OF MODULATING ADIPOCYTE DIFFERENTIATION | GENFIT (FR) | 2003-07-24 | — | — | WO | disclosed |
| US-5756467-A | USEFUL IN PREVENTION AND THERAPY OF OBESITY AND CARDIOVASCULAR DISEASES IN HUMANS AND ANIMALS; ADMINISTERING IN FOOD AND FEEDS | ITOHAM FOODS INC. (JP) | 1998-05-26 | — | — | US | disclosed |