SCHEMBL150602

SCHEMBL150602

CC(C)C(C)n1c(=O)[nH]c2nc[nH]c2c1=O

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 9/20 0.59
ADORA2A P29274 6/20 0.59
ADORA3 P0DMS8 6/20 0.56
PDE4A P27815 4/20 0.56
PDE4B Q07343 4/20 0.56
PDE4C Q08493 4/20 0.56
PDE4D Q08499 4/20 0.56
ACHE P22303 1/20 0.41
GDA Q9Y2T3 1/20 0.41
ABL1 P00519 1/20 0.38
RIN1 Q13671 1/20 0.38
ADORA1 P30542 1/20 0.38
ATAD2 Q6PL18 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12413533 0.87 ADORA2B (0.63) ADORA2BADORA2AADORA3PDE4APDE4B
SCHEMBL10535015 0.82 ADORA2A (0.57) ADORA2BADORA2AADORA3PDE4APDE4B
SCHEMBL897035 0.81 ADORA2B (0.55) ADORA2BADORA2AADORA3PDE4APDE4B
SCHEMBL2917584 0.81 ADORA2B (0.55) ADORA2BADORA2AADORA3PDE4APDE4B
SCHEMBL7035609 0.79 ADORA2B (0.52) ADORA2BADORA2AADORA3PDE4APDE4B
SCHEMBL7801074 0.76 ADORA2B (0.56) ADORA2BADORA2AADORA3PDE4APDE4B
SCHEMBL3489064 0.75 ADORA2A (0.55) ADORA2BADORA2AADORA3PDE4APDE4B
1-Methylxanthine SCHEMBL10996 0.75 ADORA2B (1.00) ADORA2BADORA2AADORA3PDE4APDE4B
SCHEMBL5510062 0.75 ADORA2B (0.64) ADORA2BADORA2AADORA3PDE4APDE4B
SCHEMBL2842234 0.75 ADORA2B (0.55) ADORA2BADORA2AADORA3PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090028830-A1 Preparation of multipotent stem cells and the use thereof LIU YUNG-HSIANG 2009-01-29 US claimed
CN-101085983-A Autologous stem cell, target cell transformed therefrom and its uses YONGXIANG LIU (CN) 2007-12-12 CN claimed
EP-0954565-B1 ADIPOGENIC DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS OSIRIS THERAPEUTICS INC (US) 2006-10-11 EP claimed
WO-2004097009-A2 METHOD TO IDENTIFY AGENTS THAT ACTIVATE OR INHIBIT IKKi NOVARTIS AG (CH) 2004-11-11 WO claimed
EP-0403139-B1 Cell culture sytems and media ORGANOGENESIS INC (US) 1998-08-12 EP claimed
US-20260076966-A1 METHOD OF INHIBITING TREM-1 UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-03-19 US disclosed
EP-3946349-B1 SR-1903 FOR THE TREATMENT OF INFLAMMATORY, INNATE IMMUNE RESPONSE OR AUTOIMMUNE DISORDERS UNIV FLORIDA (US) 2026-02-25 EP disclosed
US-20260049295-A1 Targeting Nrip1 to Alleviate Metabolic Disease UNIV MASSACHUSETTS (US) 2026-02-19 US disclosed
US-12553039-B2 Targeting Nrip1 to alleviate metabolic disease UNIVERSITY OF MASSACHUSETTS (US) 2026-02-17 US disclosed
EP-4692301-A1 CELL CHARACTERIZATION, TYPING AND IDENTIFICATION METHOD AND USE Yigong Ruixin (Xiamen) Technology Co., Ltd (CN) 2026-02-11 EP disclosed
US-20260035666-A1 ENHANCED MSC PREPARATIONS MESOBLAST INT SARL (CH) 2026-02-05 US disclosed
US-20260016464-A1 METHOD FOR CHARACTERIZING, TYPING AND IDENTIFYING CELLS AND USE THEREOF YIGONG RUIXIN (XIAMEN) TECHNOLOGY CO., LTD (CN) 2026-01-15 US disclosed
US-4764502-A FERTILITY INHIBITION UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1988-08-16 US disclosed
EP-0212489-A2 Anabolic activity modulator and uses thereof THE ROCKEFELLER UNIVERSITY (US) 1987-03-04 EP disclosed
EP-0178841-A2 Intragonadal regulatory protein UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1986-04-23 EP disclosed
US-4579865-A ANTIISCHEMIC, HYPOGLYCEMIC AGENTS USV PHARMACEUTICAL CORP. (US) 1986-04-01 US disclosed
EP-0175005-A1 5,6,7-Quinoline carbamates USV PHARMACEUTICAL CORPORATION (US) 1986-03-26 EP disclosed
US-4547509-A TREATMENT OF HYPERTRIGLYCERIDEMIA USV PHARMACEUTICAL CORP. (US) 1985-10-15 US disclosed
US-4530931-A 8-Quinoline carbanilates for the inhibition of lipolysis USV PHARMACEUTICAL CORP. (US) 1985-07-23 US disclosed
US-4508828-A Bioassay of parathyroid hormone IMMUNO NUCLEAR CORPORATION (US) 1985-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049295-A1 Targeting Nrip1 to Alleviate Metabolic Disease NR0B1, NR5A2, PLIN1 ADORA2B 2121/4885ADORA2A 1131/4885ADORA3 1657/4885
US-20260076966-A1 METHOD OF INHIBITING TREM-1 NR5A1, NR3C1, NR1H3 ADORA2B 1270/4885ADORA2A 1279/4885ADORA3 339/4885
US-12553039-B2 Targeting Nrip1 to alleviate metabolic disease SREBF1, NR1I2, NR5A2 ADORA2B 2928/4885ADORA2A 1737/4885ADORA3 2651/4885
US-20260016464-A1 METHOD FOR CHARACTERIZING, TYPING AND IDENTIFYING CELLS AND USE THEREOF ITGB4, HTR3D, EPCAM ADORA2B 623/4885ADORA2A 902/4885ADORA3 625/4885
US-20260035666-A1 ENHANCED MSC PREPARATIONS CD40, ICOS, CD63 ADORA2B 1083/4885ADORA2A 386/4885ADORA3 562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.