Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.83 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL513767 | 1.00 | AKR1B1 (0.83) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Ethylenediamine SCHEMBL28145957 | 0.98 | AKR1B1 (0.80) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Putrescine SCHEMBL9393794 | 0.92 | AKR1B1 (0.77) | AKR1B1TAAR1TDP1HSPA5TTR | |
| SCHEMBL30449014 | 0.91 | AKR1B1 (1.00) | AKR1B1TAAR1TDP1HSPA5TTR | |
| SCHEMBL72309 | 0.91 | AKR1B1 (1.00) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Potassium SCHEMBL4278025 | 0.89 | AKR1B1 (0.95) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Phosphine SCHEMBL28850721 | 0.89 | AKR1B1 (0.95) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Hydrochloric Acid SCHEMBL8622012 | 0.89 | AKR1B1 (0.95) | AKR1B1TDP1HSPA5TTRCXCL8 | |
| SCHEMBL4284420 | 0.89 | AKR1B1 (0.95) | AKR1B1TAAR1TDP1HSPA5TTR | |
| SCHEMBL28407811 | 0.89 | AKR1B1 (0.95) | AKR1B1TAAR1TDP1HSPA5TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011215-A1 | MATERIALS AND METHODS FOR REMEDIATING AND MITIGATING IRON POLLUTION | LOCUS SOLUTIONS IPCO, LLC (US) | 2024-01-11 | — | — | WO | claimed |
| WO-2024011207-A1 | MATERIALS AND METHODS FOR IRON CAPTURE AND GREENHOUSE GAS REDUCTION | LOCUS SOLUTIONS IPCO, LLC (US) | 2024-01-11 | — | — | WO | claimed |
| WO-2024011222-A1 | MATERIALS AND METHODS FOR TREATING IRON DEFICIENCIES AND IRON CHLOROSIS IN PLANTS | LOCUS SOLUTIONS IPCO, LLC (US) | 2024-01-11 | — | — | WO | claimed |
| WO-2016010439-A1 | CONTROLLING MICROBIAL INFECTION IN PLANTS | SEEKA KIWIFRUIT INDUSTRIES LIMITED (NZ) | 2016-01-21 | — | — | WO | claimed |
| EP-0486499-B1 | STABLE ASCORBIC ACID COMPOSITIONS | UNIV DUKE (US) | 1997-08-06 | — | — | EP | claimed |
| EP-0486499-A4 | STABLE ASCORBIC ACID COMPOSITIONS | — | 1993-06-16 | — | — | EP | claimed |
| EP-0486499-A1 | STABLE ASCORBIC ACID COMPOSITIONS. | UNIV DUKE (US) | 1992-05-27 | — | — | EP | claimed |
| WO-1990012572-A1 | STABLE ASCORBIC ACID COMPOSITIONS | DUKE UNIVERSITY (US) | 1990-11-01 | — | — | WO | claimed |
| US-4412943-A | CONTAINING AN ALKYLENEDIAMINE CARBOXYLIC ACID DERIVATIVE AND AN AMMONIUM SULFATE | KAO SOAP CO., LTD. (JP) | 1983-11-01 | — | — | US | claimed |
| US-4219349-A | PLANT NUTRIENTS ATTACHED TO CALCINED CLAYS | MALLINCKRODT, INC. (US) | 1980-08-26 | — | — | US | claimed |
| US-4192722-A | Composition and method for stannate plating of large aluminum parts | REYNOLDS METALS COMPANY (US) | 1980-03-11 | — | — | US | claimed |
| US-12031044-B2 | Process for preparing whitened fly ash | VECOR IP HOLDINGS LIMITED (HK) | 2024-07-09 | — | — | US | disclosed |
| WO-2024011207-A1 | MATERIALS AND METHODS FOR IRON CAPTURE AND GREENHOUSE GAS REDUCTION | LOCUS SOLUTIONS IPCO, LLC (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2024011212-A1 | MATERIALS AND METHODS FOR CONTROL OF IRON-CAPTURING PATHOGENS | LOCUS SOLUTIONS IPCO, LLC (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2024011215-A1 | MATERIALS AND METHODS FOR REMEDIATING AND MITIGATING IRON POLLUTION | LOCUS SOLUTIONS IPCO, LLC (US) | 2024-01-11 | — | — | WO | disclosed |
| US-4219349-A | PLANT NUTRIENTS ATTACHED TO CALCINED CLAYS | MALLINCKRODT, INC. (US) | 1980-08-26 | — | — | US | disclosed |
| US-4067836-A | ETHYLENE POLYMER, AUTO-OXIDATIVE COMPOUND, METAL SALTS | UNION CARBIDE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-3961932-A | COMPLEXES OF SYNTHETIC AMINO ACID CHELATING AGENTS WITH ZINC, COPPER OR MANGANESE | CIBA-GEIGY CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
| US-3958972-A | Chelates of 1,2-diaminocyclohexane tetrakis (methylene phosphonic acid) useful for supplying nutrient metals to plants growing in calcareous soil | MONSANTO COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
| US-3935141-A | METAL SALT, ANTIOXIDANT | UNION CARBIDE CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |