Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.83 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL3489186 | 1.00 | AKR1B1 (0.83) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Ethylenediamine SCHEMBL28145957 | 0.98 | AKR1B1 (0.80) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Putrescine SCHEMBL9393794 | 0.92 | AKR1B1 (0.77) | AKR1B1TAAR1TDP1HSPA5TTR | |
| SCHEMBL30449014 | 0.91 | AKR1B1 (1.00) | AKR1B1TAAR1TDP1HSPA5TTR | |
| SCHEMBL72309 | 0.91 | AKR1B1 (1.00) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Potassium SCHEMBL4278025 | 0.89 | AKR1B1 (0.95) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Phosphine SCHEMBL28850721 | 0.89 | AKR1B1 (0.95) | AKR1B1TAAR1TDP1HSPA5TTR | |
| Hydrochloric Acid SCHEMBL8622012 | 0.89 | AKR1B1 (0.95) | AKR1B1TDP1HSPA5TTRCXCL8 | |
| SCHEMBL4284420 | 0.89 | AKR1B1 (0.95) | AKR1B1TAAR1TDP1HSPA5TTR | |
| SCHEMBL28407811 | 0.89 | AKR1B1 (0.95) | AKR1B1TAAR1TDP1HSPA5TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114631655-A | Mask for resisting bacteria and viruses and isolating harmful substances | 福美来堂股份有限公司 | 2022-06-17 | — | — | CN | claimed |
| CN-111592425-A | Modified seaweed functional water-soluble fertilizer and preparation method thereof | 青岛埃图生物科技有限公司 | 2020-08-28 | — | — | CN | claimed |
| CN-111302869-A | Modified humic acid functional water-soluble fertilizer and preparation method thereof | 青岛埃图作物营养有限公司 | 2020-06-19 | — | — | CN | claimed |
| CN-109169107-A | A kind of novel Rhizoma Gastrodiae implantation methods | 英山县祥友瓜蒌专业合作社 | 2019-01-11 | — | — | CN | claimed |
| CN-107484530-A | A kind of implantation methods of rhizoma Gastrodiae | 安徽亚泰天然植物科技有限公司 | 2017-12-19 | — | — | CN | claimed |
| CN-106954443-A | A kind of new rhizoma Gastrodiae implantation methods | 彝良县洪述天麻开发有限责任公司 | 2017-07-18 | — | — | CN | claimed |
| CN-106831885-A | The preparation method of ethylenediamine o-hydroxy phenylacetic acid ferrisodium | 四川隆桥化工集团有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-106396904-A | Nutritional fertility enhancer for improving secondary saline land | 山东胜伟园林科技有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-106386047-A | Method for planting corn in saline-alkali land in Hetao irrigation area | 山东胜伟园林科技有限公司 | 2017-02-15 | — | — | CN | claimed |
| US-20160136784-A1 | Polishing Composition and Polishing Method | FUJIMI INCORPORATED (JP) | 2016-05-19 | — | — | US | claimed |
| US-20140227366-A1 | CARRIER MATERIAL FOR IMPROVING THE PERSISTANCE OF BIOCIDES | ARPOLITH GMBH (DE) | 2014-08-14 | — | — | US | claimed |
| CN-110838450-B | Processing method of packaging substrate | 株式会社迪思科 | 2024-05-24 | — | — | CN | disclosed |
| CN-117693563-A | Aqueous dispersion comprising inorganic particles | 碧德·奧利珍股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117621283-A | Cutting device | 株式会社迪思科 | 2024-03-01 | — | — | CN | disclosed |
| CN-108695145-B | Processing method | 株式会社迪思科 | 2024-02-20 | — | — | CN | disclosed |
| US-4798783-A | NITROGEN-CONTAINING FUSED HETEROCYCLE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-01-17 | — | — | US | disclosed |
| EP-0293011-A2 | Method of processing silver halide color photographic photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |
| US-4778746-A | COLOR DEVELOPING, FIXING, STABILIZATION WITHOUT WASHING | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0266797-A2 | Method of processing silver halide color photographic material and photographic color developing composition | FUJI PHOTO FILM CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |
| EP-0255726-A2 | Method for processing a silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140227366-A1 | CARRIER MATERIAL FOR IMPROVING THE PERSISTANCE OF BIOCIDES | BSG, PGLS, GUSB | AKR1B1 2976/4885TAAR1 2935/4885TDP1 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.