Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 19/20 | 0.81 |
| ▸ | PGR | P06401 | 15/20 | 0.81 |
| ▸ | AR | P10275 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302163 | 0.96 | NR3C2 (0.74) | NR3C2PGRARPOLBMAPT | |
| SCHEMBL3489453 | 0.91 | NR3C2 (0.84) | NR3C2PGRAR | |
| SCHEMBL3489841 | 0.90 | NR3C2 (0.82) | NR3C2PGRAR | |
| SCHEMBL4295520 | 0.90 | NR3C2 (0.74) | NR3C2PGRAR | |
| SCHEMBL3488719 | 0.89 | NR3C2 (1.00) | NR3C2PGRAR | |
| SCHEMBL3491040 | 0.88 | NR3C2 (0.81) | NR3C2PGRAR | |
| SCHEMBL4296087 | 0.87 | NR3C2 (0.77) | NR3C2PGRARMAPT | |
| SCHEMBL4298037 | 0.87 | NR3C2 (0.80) | NR3C2PGRAR | |
| SCHEMBL3491058 | 0.86 | NR3C2 (0.86) | NR3C2PGRAR | |
| SCHEMBL4297101 | 0.86 | NR3C2 (0.76) | NR3C2PGRARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094000-A1 | PYRAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20100094000-A1 | PYRAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20100094000-A1 | PYRAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094000-A1 | PYRAZOLE COMPOUNDS | NR3C2, MC2R, NR3C1 | NR3C2 1/4885PGR 107/4885AR 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.