Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28728652 | 0.85 | GPR84 (0.52) | FFAR1FFAR4GPR84PTPN1ALDH1A1 | |
| SCHEMBL17986393 | 0.85 | GPR84 (0.52) | FFAR1FFAR4GPR84PTPN1ALDH1A1 | |
| SCHEMBL29033660 | 0.85 | GPR84 (0.52) | FFAR1FFAR4GPR84PTPN1ALDH1A1 | |
| SCHEMBL2229251 | 0.85 | GPR84 (0.52) | FFAR1FFAR4GPR84PTPN1ALDH1A1 | |
| SCHEMBL580357 | 0.85 | GPR84 (0.52) | FFAR1FFAR4GPR84PTPN1ALDH1A1 | |
| SCHEMBL28126407 | 0.81 | GPR84 (0.47) | FFAR1FFAR4GPR84MAPT | |
| SCHEMBL28311963 | 0.81 | GPR84 (0.47) | FFAR1FFAR4GPR84ALDH1A1MAPT | |
| SCHEMBL5745236 | 0.80 | GPR84 (0.37) | FFAR1FFAR4GPR84PTPN1 | |
| SCHEMBL28342079 | 0.80 | ALDH1A1 (0.42) | FFAR1FFAR4GPR84ALDH1A1MAPT | |
| SCHEMBL20550999 | 0.79 | GPR84 (0.48) | FFAR1GPR84ALDH1A1MAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100074991-A1 | NOVEL OXIDOREDUCTASES AND USES THEREOF | DSM IP ASSETS B.V. (NL) | 2010-03-25 | — | — | US | disclosed |
| EP-1987139-A2 | NOVEL OXIDOREDUCTASES AND USES THEREOF | DSMIP Assets B.V. (NL) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007090675-A2 | NOVEL OXIDOREDUCTASES AND USES THEREOF | DSM IP ASSETS B.V. (NL) | 2007-08-16 | — | — | WO | disclosed |