Hexamethonium

Hexamethonium

SCHEMBL34900

C[N+](C)(C)CCCCCC[N+](C)(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
ACHE P22303 4/20 1.00
APEX1 P27695 3/20 1.00
NFKB1 P19838 2/20 1.00
KDM4E B2RXH2 2/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
PMP22 Q01453 2/20 1.00
LMNA P02545 2/20 1.00
HSD17B10 Q99714 1/20 1.00
HRH3 Q9Y5N1 1/20 1.00
TSHR P16473 1/20 1.00
RAB9A P51151 1/20 1.00
NPSR1 Q6W5P4 1/20 0.92
DNM1 Q05193 6/20 0.73
APAF1 O14727 1/20 0.65
HSP90AA1 P07900 1/20 0.65
RAD52 P43351 1/20 0.65
BBOX1 O75936 1/20 0.47
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30019398 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL6933263 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL17898629 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL17898630 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL6931794 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
Decamethonium SCHEMBL238400 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL8208718 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL12126378 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
Pentamethonium SCHEMBL61798 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1
SCHEMBL12198121 1.00 MEN1 (1.00) MEN1KMT2AACHEAPEX1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11812 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743479-A1 ADENOVIRUSES Theolytics Ltd. (GB) 2026-05-20 EP claimed
CN-122012815-A Synchronous detection primer, probe and application of norovirus II, group A rotavirus and adenovirus 安徽省公共卫生临床中心(安徽省传染病医院) 2026-05-12 CN claimed
US-12623910-B2 Molecular sieve SSZ-94, catalyst, and methods of use thereof CHEVRON U.S.A. INC. (US) 2026-05-12 US claimed
US-20260117254-A1 COMPOSITIONS AND METHODS FOR PREPARING VIRAL VECTORS NIKEGEN LLC (US) 2026-04-30 US claimed
US-20260117201-A1 Polynucleotides for use in AAV production ENCODED THERAPEUTICS INC (US) 2026-04-30 US claimed
US-12611658-B2 Molecular sieve SSZ-93, catalyst, and methods of use thereof CHEVRON U.S.A. INC. (US) 2026-04-28 US claimed
EP-4728440-A2 IDENTIFYING MINIMUM-ENERGY RESONANCE REGION AT MAJORANA ISLAND Microsoft Technology Licensing, LLC (US) 2026-04-22 EP claimed
EP-4705954-A2 JOINT PARITY MEASUREMENTS OF MAJORANA ZERO MODES IN THE PRESENCE OF QUASIPARTICLE POISONING Microsoft Technology Licensing, LLC (US) 2026-03-11 EP claimed
US-20260042675-A1 MOLECULAR SIEVE SSZ-91 WITH HIERARCHICAL POROSITY, METHODS FOR PREPARING, AND USES THEREOF CHEVRON USA INC (US) 2026-02-12 US claimed
EP-4689137-A1 COMPOSITIONS AND METHODS FOR RECOMBINANT AAV PRODUCTION REGENXBIO Inc. (US) 2026-02-11 EP claimed
US-5016652-A Dermally Applicable Patch THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-05-21 US claimed
EP-0333769-A4 COMBINATIONS OF RENAL VASODILATORS AND ALPHA 1-ADRENERGIC OR GANGLIONIC BLOCKING AGENTS FOR TREATING DISEASES. NEW YORK MEDICAL COLLEGE (US) 1990-06-27 EP claimed
US-4920989-A Method and apparatus for aiding in the reduction of incidence of tobacco smoking REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1990-05-01 US claimed
EP-0333769-A1 COMBINATIONS OF RENAL VASODILATORS AND ALPHA 1-ADRENERGIC OR GANGLIONIC BLOCKING AGENTS FOR TREATING DISEASES NEW YORK MEDICAL COLLEGE (US) 1989-09-27 EP claimed
WO-1988004179-A1 COMBINATIONS OF RENAL VASODILATORS AND alpha1-ADRENERGIC OR GANGLIONIC BLOCKING AGENTS AND METHODS FOR TREATING DISEASES NEW YORK MEDICAL COLLEGE (US) 1988-06-16 WO claimed
US-4749686-A Combinations of renal vasodilators and α1 -adrenergic or ganglionic blocking agents and methods for treating diseases NEW YORK MEDICAL COLLEGE (US) 1988-06-07 US claimed
US-4581376-A ALPHA-ADRENERGIC ANTAGONISTS, HYPOTENSIVE AGENTS FOR GLAUCOMA AND DECONGESTANTS MACRI FRANK J (US) 1986-04-08 US claimed
US-4487829-A Production and use of monoclonal antibodies against adenoviruses MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1984-12-11 US claimed
EP-0126327-A1 Norepinephrine potentiated pharmaceutical composition, ophthalmic solution and kit containing the same Macri, Frank J. (US) 1984-11-28 EP claimed
EP-0051318-A1 A catalyst composition containing as catalytically active components alumina and a cristalline Aluminosilicate zeolite, a process for isomerizing xylenes and ethylbenzene, and use of this catalyst composition Teijin Petrochemical Industries Ltd. (JP) 1982-05-12 EP claimed