Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11966094 | 1.00 | KDM4D (0.48) | KDM4DNAMPTNAAAKMT2AMEN1 | |
| SCHEMBL11966093 | 0.90 | KDM4D (0.48) | KDM4DKMT2ACKS1BSKP1SKP2 | |
| SCHEMBL3490526 | 0.90 | KDM4D (0.48) | KDM4DKMT2ACKS1BSKP1SKP2 | |
| SCHEMBL11966095 | 0.88 | CYP17A1 (0.51) | KDM4DNAMPTKMT2AMEN1RAB9A | |
| SCHEMBL12678778 | 0.84 | KDM4D (0.46) | KDM4DCKS1BSKP1SKP2KDM1A | |
| SCHEMBL4784323 | 0.84 | KDM4D (0.46) | KDM4DCKS1BSKP1SKP2KDM1A | |
| SCHEMBL23124584 | 0.82 | MEN1 (0.66) | NAAAKMT2AMEN1RAB9AKDM1A | |
| SCHEMBL14204945 | 0.81 | KDM4D (0.47) | KDM4DKMT2ACKS1BSKP1SKP2 | |
| SCHEMBL22819319 | 0.81 | KDM4D (0.47) | KDM4DKMT2ACKS1BSKP1SKP2 | |
| SCHEMBL11966092 | 0.81 | KDM4D (0.47) | KDM4DKMT2ACKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242142-B2 | Cyclohexylamines, phenylamines and uses thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-14 | — | — | US | disclosed |
| US-20100048637-A1 | CYCLOHEXYLAMINES, PHENYLAMINES AND USES THEREOF | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048637-A1 | CYCLOHEXYLAMINES, PHENYLAMINES AND USES THEREOF | SMO, HNMT, INMT | KDM4D 651/4885NAMPT 1619/4885NAAA 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.