SCHEMBL349064

SCHEMBL349064

O=C(Cl)CCCCCCBr

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
ALDH1A1 P00352 2/20 0.56
TP53 P04637 1/20 0.48
LMNA P02545 3/20 0.36
NFKB1 P19838 1/20 0.36
PMP22 Q01453 1/20 0.36
FAAH O00519 1/20 0.34
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CES2 O00748 3/20 0.31
CES1 P23141 3/20 0.31
GPR84 Q9NQS5 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348782 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL306578 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL347793 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL347023 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL11255873 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL13859605 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL34211 1.00
SCHEMBL347787 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL305763 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL28244416 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113040145-B Preparation method of elm spot moth sex attractant 虫捕头(苏州)生物科技有限公司 2022-04-08 CN claimed
CN-113876595-A Birch alcohol-based quaternary ammonium salt antibacterial organic monomer, application of composite resin of birch alcohol-based quaternary ammonium salt antibacterial organic monomer and preparation method of composite resin of birch alcohol-based quaternary ammonium salt antibacterial organic monomer 东华大学 2022-01-04 CN claimed
CN-113040145-A Hypecox ulmoides sex attractant and preparation method thereof 虫捕头(苏州)生物科技有限公司 2021-06-29 CN claimed
EP-4687854-A2 LIPIDS AND LIPID-LIKE COMPOUNDS FOR THERAPEUTIC LIPID NANOPARTICLE (LNP) DELIVERY Flagship Labs 114, Inc. (US) 2026-02-11 EP disclosed
WO-2025108411-A1 EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京沐华生物科技有限责任公司 2025-05-30 WO disclosed
EP-4501327-A2 SUBSTITUTED PYRROLOPYRIMIDINE AND PYRAZOLOPYRIMIDINE AS BRUTON S TYROSINEKINASE (BTK) DEGRADERS Accutar Biotechnology Inc. (US) 2025-02-05 EP disclosed
CN-118878517-A ANXA3 protein targeted degradation chimeric body and preparation method and application thereof 复旦大学 2024-11-01 CN disclosed
CN-116496253-B C-MET protein targeted degradation agent and medical application thereof 中国人民解放军军事科学院军事医学研究院 2024-10-11 CN disclosed
WO-2024211865-A2 LIPIDS AND LIPID-LIKE COMPOUNDS FOR THERAPEUTIC LIPID NANOPARTICLE (LNP) DELIVERY OMEGA THERAPEUTICS, INC. (US) 2024-10-10 WO disclosed
EP-4039688-B1 SUBSTITUTED PYRROLOPYRIMIDINE AND PYRAZOLOPYRIMIDINE AS BRUTON'S TYROSINE KINASE (BTK) DEGRADERS ACCUTAR BIOTECHNOLOGY INC (US) 2024-10-09 EP disclosed
WO-2024125629-A1 UREIC COMPOUND AND PHARMACEUTICAL USE THEREOF AS STING INHIBITOR 中国药科大学 2024-06-20 WO disclosed
EP-0407217-A1 Pharmaceutically active compounds SCHERING CORPORATION (US) 1991-01-09 EP disclosed
US-4851423-A Pharmaceutically active compounds SCHERING CORPORATION (US) 1989-07-25 US disclosed
US-4835180-A N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity STERLING DRUG INC. (US) 1989-05-30 US disclosed
EP-0274867-A2 Pharmaceutically active compounds SCHERING CORPORATION (US) 1988-07-20 EP disclosed
EP-0262618-A2 N-(omega)-cyanoalkyl)aminophenols, and their preparation STERLING DRUG INC. (US) 1988-04-06 EP disclosed
US-4085219-A DIURETICS, SALURETICS, URICOSURIC AGENTS MERCK & CO., INC. (US) 1978-04-18 US disclosed
US-4081554-A DIURETICS, SALURETICS, URICOSURICS MERCK & CO., INC. (US) 1978-03-28 US disclosed
US-3984465-A DIURETIC, SALURETIC AND URICOSURIC MERCK & CO., INC. (US) 1976-10-05 US disclosed
US-3932487-A HYPOTENSIVE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-13 US disclosed