Sugi Predict

Sugi Predict / Compounds / SCHEMBL305763

SCHEMBL305763

SCHEMBL305763

O=C(Cl)CCCCCCCCCCCCCCCBr

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 4/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ TP53 P04637 1/20 0.48
▸ LMNA P02545 3/20 0.36
▸ NFKB1 P19838 1/20 0.36
▸ PMP22 Q01453 1/20 0.36
▸ FAAH O00519 1/20 0.34
▸ HDAC3 O15379 1/20 0.32
▸ HDAC1 Q13547 1/20 0.32
▸ HDAC2 Q92769 1/20 0.32
▸ HDAC8 Q9BY41 1/20 0.32
▸ HDAC6 Q9UBN7 1/20 0.32
▸ HDAC5 Q9UQL6 1/20 0.32
▸ L3MBTL1 Q9Y468 2/20 0.31
▸ MAPT P10636 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ CES2 O00748 3/20 0.31
▸ CES1 P23141 3/20 0.31
▸ GPR84 Q9NQS5 1/20 0.31
▸ FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348782 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL306578 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL347793 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL347023 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL11255873 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL13859605 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL34211 1.00 — —
SCHEMBL347787 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL349064 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL28244416 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11377445-B2 Derivatives of paliperidone and process for the preparation thereof ZENVISION PHARMA LLP (IN) 2022-07-05 — — US claimed
WO-2021070125-A1 NOVEL AMIDE DERIVATIVES OF LINAGLIPTIN AND PROCESS FOR THE PREPARATION THEREOF ZENVISION PHARMA LLP (IN) 2021-04-15 — — WO claimed
US-20200354360-A1 NOVEL DERIVATIVES OF PALIPERIDONE AND PROCESS FOR THE PREPARATION THEREOF ZENVISION PHARMA LLP (IN) 2020-11-12 — — US claimed
WO-2019162746-A1 NOVEL DERIVATIVES OF PALIPERIDONE AND PROCESS FOR THE PREPARATION THEREOF ZENVISION PHARMA LLP (IN) 2019-08-29 — — WO claimed
CN-108484687-A The preparation method of technetium-99 m labeled triphenylphosphine salt derivative and application 河南中医药大学 2018-09-04 — — CN claimed
US-11377445-B2 Derivatives of paliperidone and process for the preparation thereof ZENVISION PHARMA LLP (IN) 2022-07-05 — — US disclosed
WO-2021070125-A1 NOVEL AMIDE DERIVATIVES OF LINAGLIPTIN AND PROCESS FOR THE PREPARATION THEREOF ZENVISION PHARMA LLP (IN) 2021-04-15 — — WO disclosed
US-20200354360-A1 NOVEL DERIVATIVES OF PALIPERIDONE AND PROCESS FOR THE PREPARATION THEREOF ZENVISION PHARMA LLP (IN) 2020-11-12 — — US disclosed
WO-2019162746-A1 NOVEL DERIVATIVES OF PALIPERIDONE AND PROCESS FOR THE PREPARATION THEREOF ZENVISION PHARMA LLP (IN) 2019-08-29 — — WO disclosed
US-20190225578-A1 PROCESS FOR TREATING KERATIN FIBRES WITH A CATIONIC DISULFIDE COMPOUND L'OREAL (FR) 2019-07-25 — — US disclosed
EP-3374030-A1 PROCESS FOR TREATING KERATIN FIBRES WITH A CATIONIC DISULFIDE COMPOUND L'Oréal (FR) 2018-09-19 — — EP disclosed
CN-108484687-A The preparation method of technetium-99 m labeled triphenylphosphine salt derivative and application 河南中医药大学 2018-09-04 — — CN disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 — — US disclosed
WO-2006050265-A2 CERAMIDES AND APOPTOSIS-SIGNALING LIGAND MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2006-05-11 — — WO disclosed
WO-2006050264-A1 CATIONIC CERAMIDES, AND ANALOGS THEREOF, AND THEIR USE FOR PREVENTING OR TREATING CANCER MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2006-05-11 — — WO disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 — — US disclosed
EP-1210714-A4 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV (US) 2006-01-04 — — EP disclosed
WO-2001003126-A9 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV CALIFORNIA (US) 2002-08-01 — — WO disclosed
EP-1210714-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE The Regents of the University of California (US) 2002-06-05 — — EP disclosed
WO-2001003126-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-01-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225578-A1 PROCESS FOR TREATING KERATIN FIBRES WITH A CATIONIC DISULFIDE COMPOUND KRT18, F12, H1-0 TSHR 2690/4885ALDH1A1 2811/4885TP53 1428/4885
US-20200354360-A1 NOVEL DERIVATIVES OF PALIPERIDONE AND PROCESS FOR THE PREPARATION THEREOF RAP2C, ADH1C, FFAR2 TSHR 436/4885ALDH1A1 254/4885TP53 4356/4885
US-11377445-B2 Derivatives of paliperidone and process for the preparation thereof RAP2C, AVPR2, ADH1C TSHR 387/4885ALDH1A1 326/4885TP53 4310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.