SCHEMBL347793

SCHEMBL347793

O=C(Cl)CCCCCCCCCBr

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
ALDH1A1 P00352 2/20 0.56
TP53 P04637 1/20 0.48
LMNA P02545 3/20 0.36
NFKB1 P19838 1/20 0.36
PMP22 Q01453 1/20 0.36
FAAH O00519 1/20 0.34
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CES2 O00748 3/20 0.31
CES1 P23141 3/20 0.31
GPR84 Q9NQS5 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348782 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL306578 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL347023 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL11255873 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL13859605 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL34211 1.00
SCHEMBL347787 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL305763 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL349064 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1
SCHEMBL28244416 1.00 TSHR (0.56) TSHRALDH1A1TP53LMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111187374-B Luminescent liquid crystal polymer containing menthol chiral structure and preparation method thereof 湘潭大学 2022-02-08 CN claimed
CN-113876595-A Birch alcohol-based quaternary ammonium salt antibacterial organic monomer, application of composite resin of birch alcohol-based quaternary ammonium salt antibacterial organic monomer and preparation method of composite resin of birch alcohol-based quaternary ammonium salt antibacterial organic monomer 东华大学 2022-01-04 CN claimed
CN-111187374-A Luminescent liquid crystal polymer containing menthol chiral structure and preparation method thereof 湘潭大学 2020-05-22 CN claimed
EP-4727913-A1 LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2026-04-22 EP disclosed
US-12545695-B2 Compounds for inhibiting neovascularization factors and use thereof UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2026-02-10 US disclosed
US-20240423915-A1 LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2024-12-26 US disclosed
WO-2024259322-A1 LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2024-12-19 WO disclosed
US-20240300987-A1 TRAP1 INHIBITOR AND USE THEREOF UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) 2024-09-12 US disclosed
CN-114901290-B Compounds for inhibiting angiogenesis factors and uses thereof 蔚山科学技术院 2024-09-03 CN disclosed
EP-4357351-A1 TRAP1 INHIBITOR AND USE THEREOF Smartin Bio Inc. (KR) 2024-04-24 EP disclosed
CN-117769559-A TRAP1 inhibitors and uses thereof 斯玛特恩生物公司 2024-03-26 CN disclosed
US-20070203115-A1 Novel quaternary ammonium compounds ASAHI KASEI PHARMA CORPORATION (JP) 2007-08-30 US disclosed
US-20070190041-A1 Novel benzothiazepine and bensothiepine compounds ASHAI KASEI PHARAMA CORPORATION (JP) 2007-08-16 US disclosed
EP-1719768-A1 NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS Asahi Kasei Pharma Corporation (JP) 2006-11-08 EP disclosed
CN-1678597-A Novel quaternary ammonium compounds ASAHI KASEI PHARMA CORP (JP) 2005-10-05 CN disclosed
EP-1535913-A1 NOVEL QUATERNARY AMMONIUM COMPOUNDS Asahi Kasei Pharma Corporation (JP) 2005-06-01 EP disclosed
US-20050009805-A1 Novel quaternary ammonium compounds ASAHI KASEI PHARMA CORPORATION (JP) 2005-01-13 US disclosed
EP-0138504-B1 STEROID DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-07-20 EP disclosed
US-4659516-A ANTIESTROGENS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-21 US disclosed
EP-0138504-A2 Steroid derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203115-A1 Novel quaternary ammonium compounds SLC10A2, SLC10A1, ABCB11 TSHR 3847/4885ALDH1A1 2165/4885TP53 4416/4885
US-12545695-B2 Compounds for inhibiting neovascularization factors and use thereof VEGFA, FLT1, KDR TSHR 1611/4885ALDH1A1 268/4885TP53 4309/4885
US-20240423915-A1 LIPIDS FOR USE IN LIPID NANOPARTICLES PHOSPHO1, SGMS1, NPC1 TSHR 2216/4885ALDH1A1 785/4885TP53 2218/4885
US-20240300987-A1 TRAP1 INHIBITOR AND USE THEREOF TRAP1, PPP1R7, PPP1R15A TSHR 3222/4885ALDH1A1 3363/4885TP53 596/4885
US-20050009805-A1 Novel quaternary ammonium compounds SLC10A1, GOT1, ACAT2 TSHR 2727/4885ALDH1A1 1743/4885TP53 3898/4885
US-20070190041-A1 Novel benzothiazepine and bensothiepine compounds SLC10A1, GOT1, CES1 TSHR 2972/4885ALDH1A1 680/4885TP53 4648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.