Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3056449 | 0.67 | — | — | |
| SCHEMBL5369837 | 0.65 | — | — | |
| SCHEMBL1421603 | 0.65 | — | — | |
| SCHEMBL14855 | 0.61 | — | — | |
| SCHEMBL20661241 | 0.61 | ALDH1A1 (1.00) | ALDH1A1TP53TSHR | |
| SCHEMBL1331930 | 0.61 | — | — | |
| SCHEMBL322832 | 0.61 | ALDH1A1 (1.00) | ALDH1A1TP53TSHR | |
| SCHEMBL31707460 | 0.59 | ALDH1A1 (0.41) | ALDH1A1TP53TSHR | |
| SCHEMBL7091146 | 0.58 | — | — | |
| Bromide SCHEMBL8198603 | 0.58 | ALDH1A1 (0.91) | ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447127-B2 | Synthetic lung surfactant and use thereof | UNIVERSITY OF ROCHESTER (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140044775-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2014-02-13 | — | — | US | disclosed |
| US-8563683-B2 | Synthetic lung surfactant and use thereof | UNIVERSITY OF ROCHESTER (US) | 2013-10-22 | — | — | US | disclosed |
| US-20100055164-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2049554-A2 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | University of Rochester Medical Center (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1985619-A1 | Isospecific styrene polymerisation | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-10-29 | — | — | EP | disclosed |
| WO-2008011559-A2 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100055164-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | PHOSPHO1, SGMS1, SMPD1 | ALDH1A1 4759/4885TP53 2234/4885TSHR 2303/4885 |
| US-20140044775-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | PHOSPHO1, SGMS1, SMPD1 | ALDH1A1 4759/4885TP53 2234/4885TSHR 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.