Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MANBA | O00462 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730336 | 1.00 | MANBA (0.37) | MANBALMNATHRBHIF1A | |
| SCHEMBL13885909 | 1.00 | MANBA (0.37) | MANBALMNATHRBHIF1A | |
| SCHEMBL9838843 | 0.88 | MANBA (0.39) | MANBALMNATHRBHIF1A | |
| SCHEMBL21095391 | 0.83 | GBA1 (0.34) | — | |
| SCHEMBL21095389 | 0.83 | GBA1 (0.34) | — | |
| SCHEMBL10804987 | 0.76 | MEN1 (0.39) | — | |
| SCHEMBL14227958 | 0.75 | MANBA (0.33) | MANBALMNATHRBHIF1A | |
| SCHEMBL7152161 | 0.75 | MANBA (0.33) | MANBALMNATHRBHIF1A | |
| SCHEMBL4983732 | 0.75 | MANBA (0.33) | MANBALMNATHRBHIF1A | |
| SCHEMBL4983734 | 0.75 | MANBA (0.33) | MANBALMNATHRBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121056-A1 | PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR | HUMAN GENETIC SIGNATURES PTY. LTD. (AU) | 2010-05-13 | — | — | US | disclosed |
| US-20060014144-A1 | Pseudonucleotide comprising an intercalator | HUMAN GENETIC SIGNATURES PROPRIETARY LTD. (AU) | 2006-01-19 | — | — | US | disclosed |
| EP-1468007-A2 | PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR | Human Genetic Signatures PTY Ltd. (AU) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003052134-A2 | OLIGONUCLEOTIDES COMPRISING INTERCALATOR PSEUDONUCLEOTIDE(S) FOR DETECTION OF NUCLEIC ACIDS AND MUTANTS HEREOF | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003052133-A2 | OLIGONUCLEOTIDE ANALOGUES COMPRISING INTERCALATOR PSEUDONUCLEOTIDES | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003051901-A2 | PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003052132-A2 | LINEAR AND HAIRPIN OLIGONUCLEOTIDE ANALOGUES COMPRISING INTERCALATOR PSEUDONUCLEOTIDES | HUMAN GENETIC SIGNATURES PTY LTD (AU) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014144-A1 | Pseudonucleotide comprising an intercalator | POLN, POLRMT, SUB1 | MANBA 1616/4885LMNA 418/4885THRB 3925/4885 |
| US-20100121056-A1 | PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR | POLRMT, POLN, RNASE1 | MANBA 1525/4885LMNA 569/4885THRB 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.