Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | BLM | P54132 | 1/20 | 0.75 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tretazicar SCHEMBL29375352 | 0.86 | MAPT (1.00) | MAPTCYP3A4BLMPMP22GAA | |
| Tretazicar SCHEMBL366755 | 0.86 | MAPT (1.00) | MAPTCYP3A4BLMPMP22GAA | |
| SCHEMBL11120951 | 0.81 | MAPT (0.74) | MAPTCYP3A4BLMPMP22GAA | |
| SCHEMBL13685668 | 0.77 | MAPT (0.78) | MAPTCYP3A4BLMPMP22GAA | |
| SCHEMBL5827945 | 0.77 | MAPT (0.78) | MAPTCYP3A4BLMPMP22GAA | |
| SCHEMBL5827633 | 0.76 | MAPT (0.67) | MAPTCYP3A4BLMPMP22GAA | |
| SCHEMBL5581335 | 0.74 | MAPT (0.78) | MAPTCYP3A4BLMPMP22GAA | |
| SCHEMBL3678573 | 0.74 | MAPT (0.72) | MAPTCYP3A4BLMPMP22GAA | |
| SCHEMBL28153041 | 0.72 | KDM4E (0.61) | MAPTCYP3A4BLMPMP22GAA | |
| Tretazicar SCHEMBL5805671 | 0.71 | MAPT (0.69) | MAPTCYP3A4BLMPMP22GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075414-A1 | GROWTH OF FOREIGN CELLS AFTER CONDITIONAL AND SELECTIVE DESTRUCTION OF FETAL HOST CELLS | XIMEREX, INC. (US) | 2010-03-25 | — | — | US | disclosed |
| US-7626075-B2 | Growth of foreign cells in fetal animals facilitated by conditional and selective destruction of native host cells | XIMEREX, INC. (US) | 2009-12-01 | — | — | US | disclosed |
| EP-1855534-A4 | FACILITATED CELLULAR RECONSTITUTION OF ORGANS AND TISSUES | DIAMOND PAUL (US) | 2008-12-17 | — | — | EP | disclosed |
| EP-1855534-A2 | FACILITATED CELLULAR RECONSTITUTION OF ORGANS AND TISSUES | Diamond, Paul (US) | 2007-11-21 | — | — | EP | disclosed |
| US-20070240235-A1 | METHODS FOR SUPPORTING AND PRODUCING HUMAN CELLS AND TISSUES IN NON-HUMAN MAMMAL HOSTS | DIAMOND PAUL | 2007-10-11 | — | — | US | disclosed |
| US-20070134212-A1 | Growth of foreign cells in fetal animals facilitated by conditional and selective destruction of native host cells | XIMEREX, INC. (US) | 2007-06-14 | — | — | US | disclosed |
| WO-2006074012-A2 | FACILITATED CELLULAR RECONSTITUTION OF ORGANS AND TISSUES | DIAMOND PAUL (US) | 2006-07-13 | — | — | WO | disclosed |
| WO-2006072018-A2 | METHODS FOR SUPPORTING AND PRODUCING HUMAN CELLS AND TISSUES IN NON-HUMAN MAMMAL HOSTS | DIAMOND PAUL (US) | 2006-07-06 | — | — | WO | disclosed |
| US-20060147429-A1 | FACILITATED CELLULAR RECONSTITUTION OF ORGANS AND TISSUES | DIAMOND PAUL | 2006-07-06 | — | — | US | disclosed |
| US-20060148080-A1 | METHODS FOR SUPPORTING AND PRODUCING HUMAN CELLS AND TISSUES IN NON-HUMAN MAMMAL HOSTS | DIAMOND PAUL | 2006-07-06 | — | — | US | disclosed |
| EP-1545215-A2 | GROWTH OF FOREIGN CELLS IN FETAL ANIMALS FACILITATED BY CONDITIONAL AND SELECTIVE DESTRUCTION OF NATIVE HOST CELLS | Ximerex, Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004027029-A2 | GROWTH OF FOREIGN CELLS IN FETAL ANIMALS FACILITATED BY CONDITIONAL AND SELECTIVE DESTRUCTION OF NATIVE HOST CELLS | XIMEREX, INC. (US) | 2004-04-01 | — | — | WO | disclosed |