Tretazicar

Tretazicar

SCHEMBL366755

NC(=O)c1cc(N2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 1.00
CYP3A4 P08684 1/20 1.00
BLM P54132 1/20 1.00
PMP22 Q01453 1/20 1.00
ALDH1A1 P00352 10/20 0.54
GAA P10253 4/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
PKM P14618 1/20 0.54
HTT P42858 3/20 0.51
LMNA P02545 2/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
CTPS1 P17812 1/20 0.49
POLB P06746 1/20 0.49
NPC1 O15118 1/20 0.46
NOD1 Q9Y239 1/20 0.46
GPR174 Q9BXC1 1/20 0.45
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tretazicar SCHEMBL29375352 1.00 MAPT (1.00) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL13685668 0.88 MAPT (0.78) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL5581335 0.88 MAPT (0.78) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL5827945 0.88 MAPT (0.78) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL3492841 0.86 MAPT (0.75) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL11120951 0.85 MAPT (0.74) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL3362694 0.84 MAPT (0.72) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL446497 0.84 MAPT (0.72) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL29391567 0.84 MAPT (0.72) MAPTCYP3A4BLMPMP22ALDH1A1
SCHEMBL3678573 0.84 MAPT (0.72) MAPTCYP3A4BLMPMP22ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 540 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145990-A1 TRANS-SPLICING RNA (TSRNA) NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-05-08 US claimed
US-20240075051-A1 TRANS-SPLICING RNA (tsRNA) NATIONAL UNIVERSITY OF SINGAPORE (SG) 2024-03-07 US claimed
EP-4316477-A1 METHODS FOR TREATING CARDIAC VALVE DISEASE The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone (US) 2024-02-07 EP claimed
US-20230364222-A1 RECOMBINANT VIRUSES, SURFACE-ENGINEERED DELIVERY SYSTEMS AND RELATED METHODS DEVACELL, INC. 2023-11-16 US claimed
US-11723987-B2 Double suicide gene vector systems for stem cells UNIVERSITY OF MIAMI (US) 2023-08-15 US claimed
US-11517583-B2 Trans-splicing RNA (tsRNA) NATIONAL UNIVERSITY OF SINGAPORE (SG) 2022-12-06 US claimed
US-11517530-B2 Therapeutic agents specifically delivered by exosomes for cancer treatment THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-12-06 US claimed
US-20220333079-A1 GENETICALLY MODIFIED NK CELL LINE TRANSDUCED WITH GENE ENCODING NOVEL CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF SLBiGen, Inc. (KR) 2022-10-20 US claimed
CN-115151635-A Gene-modified NK cell lines transduced with genes encoding novel chimeric antigen receptors and uses thereof 斯比根公司 2022-10-04 CN claimed
EP-4032972-A1 GENETICALLY MODIFIED NK CELL LINE TRANSDUCED WITH GENE ENCODING NOVEL CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF Slbigen Inc. (KR) 2022-07-27 EP claimed
CN-101389320-A Using alpha-hydroxycarbonyl compounds as reducing agents MORVUS TECHNOLOGY LTD (GB) 2009-03-18 CN claimed
EP-1951213-A1 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS Morvus Technology Ltd. (GB) 2008-08-06 EP claimed
US-20070254852-A1 IMPROVED NITROREDUCTASE ENZYMES UNITED STATES DEPARTMENT OF ENERGY 2007-11-01 US claimed
WO-2007074344-A1 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS MORVUS TECHNOLOGY LIMITED (GB) 2007-07-05 WO claimed
WO-2002023185-A2 DEVICES AND METHODS FOR DIRECT ELECTRONIC READOUT OF BIOMOLECULAR INTERACTIONS ENGENEOS, INC. (US) 2002-03-21 WO claimed
US-5958682-A VIRUS-DIRECTED ENZYME PRODRUG THERAPY FOR TREATING TUMOR CELLS CONSISTING OF A VIRAL VECTOR ENCODING BACTERIAL NITROREDUCTASE CAPABLE OF CONVERTING A PRODRUG INTO A CYTOTOXIC DRUG OPERABLY LINKED TO A PROMOTER; AND THE PRODRUG CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1999-09-28 US claimed
WO-1994021118-A1 GENE-THERAPY COMPOSITION AND METHOD FOR TREATING CARCINOMAS THE UAB RESEARCH FOUNDATION (US) 1994-09-29 WO claimed
EP-0429454-A1 IMPROVEMENTS RELATING TO THE CONTROL OF NEOPLASTIC TISSUE GROWTH Roberts, John J. (GB) 1991-06-05 EP claimed
EP-0330432-A1 Improvements relating to the control of neoplastic tissue growth Roberts, John J. (GB) 1989-08-30 EP claimed
WO-1989007592-A1 IMPROVEMENTS RELATING TO THE CONTROL OF NEOPLASTIC TISSUE GROWTH ROBERTS JOHN J (GB) 1989-08-24 WO claimed