SCHEMBL3493451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3594106	0.88	PDE9A (0.78)	PDE9APDE5ABRPF1FYNMEN1
	SCHEMBL3597406	0.87	PDE9A (0.77)	PDE9APDE5AKMT2AKDM4EALDH1A1
	SCHEMBL3589280	0.81	PDE9A (0.69)	PDE9APDE5AMEN1KMT2AKDM4E
	SCHEMBL3592929	0.80	PDE9A (0.67)	PDE9APDE5ABRPF1FYNMEN1
	SCHEMBL3597195	0.80	PDE9A (0.67)	PDE9APDE5ABRPF1TLR8TLR7
	SCHEMBL3598136	0.79	PDE9A (0.66)	PDE9APDE5ABRPF1TLR8TLR7
	SCHEMBL3603820	0.78	PDE9A (0.64)	PDE9APDE5ABRPF1FYN
	SCHEMBL3491481	0.78	PDE9A (1.00)	PDE9APDE5AMEN1KMT2AALDH1A1
	SCHEMBL3592928	0.78	PDE9A (0.69)	PDE9APDE5ABRPF1MEN1KMT2A
	SCHEMBL3595019	0.77	PDE9A (0.62)	PDE9APDE5ABRPF1FYNMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.