Penciclovir

Penciclovir

SCHEMBL3494

Nc1nc(=O)c2ncn(CCC(CO)CO)c2[nH]1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TK1 P04183 2/20 0.49
KMT2A Q03164 2/20 0.46
BLM P54132 2/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
NFKB1 P19838 1/20 0.46
VCP P55072 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
GAA P10253 1/20 0.45
HPRT1 P00492 5/20 0.43
PNP P00491 7/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
EDNRA P25101 1/20 0.43
HTR2A P28223 1/20 0.43
RECQL P46063 1/20 0.43
HBB P68871 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Penciclovir SCHEMBL454089 0.95 HPRT1 (0.47) TK1KMT2ABLMMEN1ALDH1A1
Penciclovir SCHEMBL4240103 0.95 HPRT1 (0.47) TK1KMT2ABLMMEN1ALDH1A1
SCHEMBL133681 0.93 TK1 (0.43) TK1KMT2ABLMMEN1ALDH1A1
SCHEMBL769982 0.93 GAA (0.47) TK1KMT2ABLMMEN1ALDH1A1
Water SCHEMBL15532449 0.92 TK1 (0.42) TK1KMT2ABLMMEN1ALDH1A1
SCHEMBL15046000 0.90 GAA (0.42) TK1KMT2ABLMMEN1ALDH1A1
Penciclovir SCHEMBL15568622 0.89 HPRT1 (0.42) TK1KMT2ABLMMEN1ALDH1A1
SCHEMBL15045959 0.88 GAA (0.43) TK1KMT2ABLMMEN1ALDH1A1
SCHEMBL15257623 0.88 KMT2A (0.42) TK1KMT2ABLMMEN1ALDH1A1
Tiviciclovir SCHEMBL15531845 0.87 BLM (0.45) TK1KMT2ABLMMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19592 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20260139860-A1 PRODUCTS OF MANUFACTURE FOR THE TREATMENT, PREVENTION AND AMELIORATION OF MICROBIAL INFECTIONS CENTRE FOR DIGESTIVE DISEASES (AU) 2026-05-21 US claimed
US-20260137669-A1 NOVEL ENANTIOMERS OF A SERIES OF ANTIVIRAL COMPOUNDS INNOVATIVE MOLECULES GMBH (DE) 2026-05-21 US claimed
EP-4094767-B1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-20 EP claimed
CN-122031290-A Percutaneous permeation promoting system and preparation method and application thereof 北京工商大学 2026-05-15 CN claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
EP-4729525-A1 NEWLY SYNTHESIZED BORON-NITROGEN HETEROCYCLES AND THEIR CONJUGATES WITH PHARMACEUTICALLY UTILIZABLE SUBSTANCES Julius-Maximilians-Universität Würzburg (DE) 2026-04-22 EP claimed
EP-3790536-B1 NANOCONTAINERS FOR TRANSPORTING NONPOLAR, LIPOPHILIC SUBSTANCES SUCH AS ANTIBIOTICS KARLSRUHER INST TECHNOLOGIE (DE) 2026-04-22 EP claimed
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-04-16 US claimed
WO-1992013527-A1 WATER-DISPERSIBLE TABLETS THE WELLCOME FOUNDATION LIMITED (GB) 1992-08-20 WO claimed
WO-1992013859-A1 PHARMACEUTICALS SMITHKLINE BEECHAM PLC (GB) 1992-08-20 WO claimed
EP-0493770-A2 Antiherpes compositions BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1992-07-08 EP claimed
EP-0493767-A2 Synergistic combination for treating herpes infections BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1992-07-08 EP claimed
WO-1992009287-A1 COMBINATIONS OF VANILLOID COMPOUNDS AND NUCLEOSIDE ANTIVIRAL COMPOUNDS FOR TREATMENT OF HERPES INFECTIONS THE PROCTER & GAMBLE COMPANY (US) 1992-06-11 WO claimed
WO-1992000742-A1 PENCICLOVIR AND FAMCICLOVIR AND RELATED GUANINE DERIVATIVES FOR THE TREATMENT OF THE HIV-1 INFECTIONS BEECHAM GROUP PLC (GB) 1992-01-23 WO claimed
WO-1991011187-A1 PHARMACEUTICAL FORMULATION BEECHAM GROUP PLC (GB) 1991-08-08 WO claimed
CN-1053547-A pharmaceutical preparation BEECHAM GROUP PLC (GB) 1991-08-07 CN claimed
EP-0416739-A1 Pharmaceutical compositions containing penciclovir Beecham Group p.l.c. (GB) 1991-03-13 EP claimed
EP-0388049-A2 Derivatives of penciclovir for the treatment of hepatitis-B infections BEECHAM GROUP PLC (GB) 1990-09-19 EP claimed