Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | MANBA | O00462 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871363 | 0.96 | CYP1A2 (0.41) | LGALS3CYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL10877634 | 0.96 | CYP1A2 (0.41) | LGALS3CYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL1935137 | 0.96 | CYP1A2 (0.41) | LGALS3CYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL29365683 | 0.81 | LGALS3 (0.41) | LGALS3CYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL30955333 | 0.81 | LGALS3 (0.41) | LGALS3CYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL4319795 | 0.79 | LGALS3 (0.46) | LGALS3CYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL8499800 | 0.78 | NPC1 (0.39) | ALDH1A1NPC1RAB9ASLC29A1 | |
| SCHEMBL7083505 | 0.78 | NPC1 (0.39) | ALDH1A1NPC1RAB9ASLC29A1 | |
| SCHEMBL31132870 | 0.76 | LGALS3 (0.38) | LGALS3CYP1A2NFKB1THPOALDH1A1 | |
| SCHEMBL10769318 | 0.76 | TDP1 (0.39) | ALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440449-B2 | Transformed Saccharomyces cerevisiae engineered for xylose utilization | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2013-05-14 | — | — | US | disclosed |
| US-20100112658-A1 | Transformed Saccharomyces cerevisiae Engineered for Xylose Utilization | LIFESENSORS, INC. | 2010-05-06 | — | — | US | disclosed |