SCHEMBL1935137

SCHEMBL1935137

O=[N+]([O-])c1ccc([C@]2(O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
NFKB1 P19838 1/20 0.41
THPO P40225 1/20 0.41
ALDH1A1 P00352 1/20 0.41
PMP22 Q01453 1/20 0.41
LGALS3 P17931 1/20 0.40
MANBA O00462 1/20 0.39
HK1 P19367 1/20 0.38
HK2 P52789 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
TSHR P16473 1/20 0.37
GBA1 P04062 2/20 0.37
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10871363 1.00 CYP1A2 (0.41) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL10877634 1.00 CYP1A2 (0.41) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL3494618 0.96 LGALS3 (0.41) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL29365683 0.82 LGALS3 (0.41) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL30955333 0.82 LGALS3 (0.41) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL27701497 0.81 MEN1 (0.35) ALDH1A1RAB9ATP53CYP3A4HIF1A
SCHEMBL8499800 0.80 NPC1 (0.39) ALDH1A1NPC1RAB9A
SCHEMBL7083505 0.80 NPC1 (0.39) ALDH1A1NPC1RAB9A
SCHEMBL9573470 0.80 ALDH1A1 (0.42) CYP1A2NFKB1THPOALDH1A1PMP22
SCHEMBL28237927 0.78 SLC5A2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5301885-A None JP disclosed
CN-118490751-B Composition of hypoglycemic plant extract and preparation method thereof 广州科望角生物科技有限公司 2025-02-07 CN disclosed
CN-118490751-A Composition of hypoglycemic plant extract and preparation method thereof 广州科望角生物科技有限公司 2024-08-16 CN disclosed
CN-118001318-A Blood sugar control composition containing mulberry leaf and cinnamon extract and application thereof 广州科望角生物科技有限公司 2024-05-10 CN disclosed
EP-4212541-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES AND THEIR INTERMEDIATES Genzyme Corporation (US) 2023-07-19 EP disclosed
US-20220242899-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2022-08-04 US disclosed
US-11279725-B2 Oligosaccharide-protein conjugates GENZYME CORPORATION (US) 2022-03-22 US disclosed
US-10781434-B2 Methods and compositions for treatment of glycogen storage diseases and glycogen metabolism disorders VALERION THERAPEUTICS, LLC (US) 2020-09-22 US disclosed
US-20200224184-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF GLYCOGEN STORAGE DISEASES AND GLYCOGEN METABOLISM DISORDERS VALERION THERAPEUTICS, LLC 2020-07-16 US disclosed
US-20200216485-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION 2020-07-09 US disclosed
WO-2010075010-A2 OLIGOSACCHARIDE-PROTEIN CONJUGATES GENZYME CORPORATION (US) 2010-07-01 WO disclosed
US-20080301826-A1 NOVEL BETA-ACTIN AND RPS21 PROMOTERS AND USES THEREOF GENZYME CORPORATION 2008-12-04 US disclosed
US-7423135-B2 Expression vector comprising rodent regulatory sequences for use as gene expression control tools in genetic engineering GENZYME CORPORATION (US) 2008-09-09 US disclosed
EP-1639112-A2 NOVEL BETA-ACTIN AND RPS21 PROMOTERS AND USES THEREOF Genzyme Corporation (US) 2006-03-29 EP disclosed
US-20050026252-A1 Expression vector comprising rodent regulatory sequences for use as gene expression control tools in genetic engineering GENZYME CORPORATION 2005-02-03 US disclosed
WO-2005000888-A2 NOVEL β-ACTIN AND RPS21 PROMOTERS AND USES THEREOF GENZYME CORPORATION (US) 2005-01-06 WO disclosed
EP-0871854-A2 MEDIUM FOR DETECTING ENTEROCOCCI IN A SAMPLE IDEXX LABORATORIES, INC. (US) 1998-10-21 EP disclosed
WO-1996015435-A2 MEDIUM FOR DETECTING ENTEROCOCCI IN A SAMPLE IDEXX LABORATORIES, INC. (US) 1996-05-23 WO disclosed
JP-H05301885-A PRODUCTION OF ALPHA-D-GLUCOPYRANOSIDE DERIVATIVE TAOKA CHEM CO LTD 1993-11-16 JP disclosed
EP-0085348-A1 Reagents for the determination of enzymes AMERICAN HOECHST CORPORATION (US) 1983-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220242899-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 CYP1A2 4094/4885NFKB1 4251/4885THPO 1718/4885
US-20200216485-A1 OLIGOSACCHARIDE-PROTEIN CONJUGATES MAN2B1, GAA, GBA1 CYP1A2 4094/4885NFKB1 4251/4885THPO 1718/4885
US-11279725-B2 Oligosaccharide-protein conjugates MAN2B1, GAA, GBA1 CYP1A2 4094/4885NFKB1 4251/4885THPO 1718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.