Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.34 |
| ▸ | NPY1R | P25929 | 5/20 | 0.34 |
| ▸ | NPY2R | P49146 | 3/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005035 | 0.83 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL13949746 | 0.83 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL23048407 | 0.83 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL3203673 | 0.82 | NOS1 (0.38) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| Hydrochloric Acid SCHEMBL28825330 | 0.81 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| Hydrochloric Acid SCHEMBL7302869 | 0.81 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| Hydrochloric Acid SCHEMBL7303864 | 0.81 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL27681071 | 0.81 | NOS1 (0.37) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL27554606 | 0.80 | CAD (0.39) | NPY4RNPY1RNPY2RNPY5RALOX15 | |
| SCHEMBL8019370 | 0.80 | CAD (0.39) | NPY4RNPY1RNPY2RNPY5RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254735-B2 | Prevention of tissue ischemia and related methods | The United States of America, as represented by the Secretary, Depar tment of Health and Human Services (US) | 2022-02-22 | — | — | US | disclosed |
| US-20200095306-A1 | PREVENTION OF TISSUE ISCHEMIA AND RELATED METHODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2020-03-26 | — | — | US | disclosed |
| US-10370439-B2 | Prevention of tissue ischemia and related methods | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-08-06 | — | — | US | disclosed |
| EP-3424950-A1 | PREVENTION OF TISSUE ISCHEMIA, RELATED METHODS AND COMPOSITIONS | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-2076537-B1 | PREVENTION OF TISSUE ISCHEMIA, RELATED METHODS AND COMPOSITIONS | US GOV HEALTH & HUMAN SERVICES (US) | 2018-08-22 | — | — | EP | disclosed |
| EP-2695896-B1 | Prevention of tissue ischemia, related methods and compositions | US GOV HEALTH & HUMAN SERVICES (US) | 2018-08-22 | — | — | EP | disclosed |
| US-20160222097-A1 | PREVENTION OF TISSUE ISCHEMIA AND RELATED METHODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) | 2016-08-04 | — | — | US | disclosed |
| US-8865672-B2 | Prevention of tissue ischemia and related methods | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2014-10-21 | — | — | US | disclosed |
| EP-2695896-A2 | Prevention of tissue ischemia, related methods and compositions | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2014-02-12 | — | — | EP | disclosed |
| US-8557788-B2 | Prevention of tissue ischemia and related compositions | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-10-15 | — | — | US | disclosed |
| US-20120295957-A1 | PREVENTION OF TISSUE ISCHEMIA AND RELATED COMPOSITIONS | WASHINGTON UNIVERSITY | 2012-11-22 | — | — | US | disclosed |
| US-20120295956-A1 | PREVENTION OF TISSUE ISCHEMIA AND RELATED METHODS | WASHINGTON UNIVERSITY | 2012-11-22 | — | — | US | disclosed |
| US-8236313-B2 | Prevention of tissue ischemia, related methods and compositions | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-08-07 | — | — | US | disclosed |
| US-20100092467-A1 | PREVENTION OF TISSUE ISCHEMIA, RELATED METHODS AND COMPOSITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-15 | — | — | US | disclosed |
| EP-2076537-A2 | PREVENTION OF TISSUE ISCHEMIA, RELATED METHODS AND COMPOSITIONS | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008060785-A9 | PREVENTION OF TISSUE ISCHEMIA, RELATED METHODS AND COMPOSITIONS | US GOV HEALTH & HUMAN SERV (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008060785-A2 | PREVENTION OF TISSUE ISCHEMIA, RELATED METHODS AND COMPOSITIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-05-22 | — | — | WO | disclosed |