Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3495310 | 1.00 | KIF11 (0.73) | KIF11 | |
| SCHEMBL1041861 | 0.91 | KIF11 (0.69) | KIF11 | |
| SCHEMBL1042900 | 0.90 | KIF11 (0.68) | KIF11 | |
| SCHEMBL3493238 | 0.89 | KIF11 (0.59) | KIF11 | |
| SCHEMBL3493245 | 0.89 | KIF11 (0.59) | KIF11 | |
| SCHEMBL1043385 | 0.88 | KIF11 (0.71) | KIF11 | |
| SCHEMBL3494990 | 0.88 | KIF11 (0.71) | KIF11 | |
| SCHEMBL3494994 | 0.88 | KIF11 (0.71) | KIF11 | |
| SCHEMBL1043725 | 0.85 | KIF11 (0.70) | KIF11 | |
| SCHEMBL13742274 | 0.83 | KIF11 (0.78) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093767-A1 | Mitotic Kinase Inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-04-15 | — | — | US | claimed |
| US-20100093767-A1 | Mitotic Kinase Inhibitors | TAKEDA SAN DIEGO, INC. (US) | 2010-04-15 | — | — | US | disclosed |
| WO-2006060737-A2 | MITOTIC KINESIN INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093767-A1 | Mitotic Kinase Inhibitors | BUB1B, BUB1, PLK1 | KIF11 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.