Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Biperiden. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 7/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 7/20 | 1.00 |
| ▸ | CHRM3 | P20309 | 6/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 5/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | HRH1 | P35367 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.61 |
| ▸ | HTR1A | P08908 | 3/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.61 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.61 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biperiden SCHEMBL20229360 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL20229362 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL20211718 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL6775788 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL16449749 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL13898507 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL23697535 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL18281117 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL16449751 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 | |
| Biperiden SCHEMBL18281119 | 1.00 | CYP2D6 (1.00) | CYP2D6CHRM2CHRM1CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11690 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607938-B1 | PHARMACEUTICAL COMPOSITION | SOVIC BRKICIC LJILJANA (HR) | 2026-05-27 | — | — | EP | claimed |
| WO-2026100654-A1 | NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD | 株式会社インファーマシア | 2026-05-15 | — | — | WO | claimed |
| EP-4724049-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | Catalent Ontario Limited (CA) | 2026-04-15 | — | — | EP | claimed |
| US-12550885-B2 | Red blood cell storage solutions, solution additives, and methods for improving the storage of red blood cells | UNIVERSITY OF CINCINNATI (US) | 2026-02-17 | — | — | US | claimed |
| US-20260027178-A1 | Treatment Of Parkinson's Disease With SIM BHLH Transcription Factor 2 (SIM2) Agonists | REGENERON PHARMA (US) | 2026-01-29 | — | — | US | claimed |
| EP-3507371-B1 | COMPOSITIONS FOR TREATING DISEASES AND DISORDERS OF THE NERVOUS SYSTEM | UNIV RUTGERS (US) | 2026-01-28 | — | — | EP | claimed |
| EP-4673215-A1 | GBA1 AND GCS DUAL MODULATOR | ONO Pharmaceutical Co., Ltd. (JP) | 2026-01-07 | — | — | EP | claimed |
| US-12514856-B2 | Pediatric trazodone compositions and method of treatment thereof | ANGELINI S.P.A. (IT) | 2026-01-06 | — | — | US | claimed |
| US-20260000910-A1 | METHOD FOR TREATING PARKINSON'S DISEASE THROUGH PHOTOSTIMULATION, AND DEVICE USED IN SAID METHOD | TSUBOTA LAB INC (JP) | 2026-01-01 | — | — | US | claimed |
| EP-4658278-A1 | SELECTIVE FIASMA TREATMENT | Valo Health, Inc. (US) | 2025-12-10 | — | — | EP | claimed |
| US-5039528-A | EAA antagonists as anti-emetic drugs | OLNEY JOHN W (US) | 1991-08-13 | — | — | US | claimed |
| US-5034400-A | N-methyl-D-aspartate antagonist for side effect reduction | OLNEY JOHN W (US) | 1991-07-23 | — | — | US | claimed |
| EP-0432994-A2 | Excitatory amino acid antagonists as anti-emetic drugs | Olney, John William (US) | 1991-06-19 | — | — | EP | claimed |
| EP-0424179-A2 | Use of combined excitatory amino acid and cholinergic antagonists to prevent neurological deterioration | Olney, John William (US) | 1991-04-24 | — | — | EP | claimed |
| US-4996047-A | Sustained release drug-resin complexes | RICHARDSON-VICKS, INC. (US) | 1991-02-26 | — | — | US | claimed |
| US-4988710-A | Anticonvulsants, anticholinergic agents, aryl-cycloalkanolamines | WASHINGTON UNIVERSITY (US) | 1991-01-29 | — | — | US | claimed |
| EP-0380989-A2 | Plaster for transdermal administration | KNOLL AG (DE) | 1990-08-08 | — | — | EP | claimed |
| US-4945097-A | THERAPY FOR ANOXIA, HYPOXIA, OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1990-07-31 | — | — | US | claimed |
| EP-0367746-A2 | Sustained release drug-resin complexes | RICHARDSON-VICKS, INC. (US) | 1990-05-09 | — | — | EP | claimed |
| US-4863738-A | TRANSDERMAL DRUG DELIVERY | ALZA CORPORATION (US) | 1989-09-05 | — | — | US | claimed |