SCHEMBL3495778

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13328614	0.86	CA12 (0.51)	DPP4ALDH1A1CA12CA1CA2
	SCHEMBL197186	0.84	DPP4 (0.49)	DPP4KDM4EALDH1A1CA12CA1
	SCHEMBL4123831	0.83	DPP4 (0.51)	DPP4KDM4EALDH1A1CA12CA1
	SCHEMBL21502002	0.83	MLYCD (0.50)	DPP4ALDH1A1CYP1A2CYP2C19LMNA
	SCHEMBL2538454	0.83	ALDH1A1 (0.47)	DPP4KDM4EALDH1A1CA12CA1
	SCHEMBL27150109	0.82	DPP4 (0.50)	DPP4KDM4EALDH1A1CA12CA1
	SCHEMBL3128273	0.82	EPHX2 (0.50)	KDM4ELMNAHPGDMEN1HTT
	SCHEMBL8251185	0.81	MAPT (0.54)	KDM4EALDH1A1CA12CA1CA2
	SCHEMBL13841059	0.81	KDM4E (0.57)	DPP4KDM4EALDH1A1CA12CA1
	SCHEMBL25017929	0.81	HRH4 (0.43)	DPP4LMNAHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.