SCHEMBL3496904

SCHEMBL3496904

CCOC([C]=O)OC(C)N

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1682635 0.78
SCHEMBL1792660 0.72
SCHEMBL3496906 0.70 MEN1 (0.32) THRB
SCHEMBL5698885 0.69
SCHEMBL27735229 0.69
SCHEMBL14980830 0.67
SCHEMBL37218 0.67
SCHEMBL945319 0.66
SCHEMBL28494631 0.65 LMNA (0.52) LMNATHRB
SCHEMBL9660243 0.65 CYP3A4 (0.33) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100112619-A1 LIGAND-CONTAINING MICELLES AND USES THEREOF GRAHAM RONALD J 2010-05-06 US disclosed
EP-1537230-A4 FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS APPLERA CORP (US) 2008-06-18 EP disclosed
EP-1687635-A2 LIGAND-CONTAINING MICELLES AND USES THEREOF Applera Corporation (US) 2006-08-09 EP disclosed
CN-1697880-A Fluorogenic enzyme assay methods and compositions APPLERA CORP (US) 2005-11-16 CN disclosed
US-20050244891-A1 Ligand-containing micelles and uses thereof APPLERA CORPORATION (US) 2005-11-03 US disclosed
WO-2005054495-A2 LIGAND-CONTAINING MICELLES AND USES THEREOF APPLERA CORPORATION (US) 2005-06-16 WO disclosed
EP-1537230-A1 FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS Applera Corporation (US) 2005-06-08 EP disclosed
US-20040146959-A1 Fluorescent enzyme assay methods and compositions APPLIED BIOSYSTEMS, LLC 2004-07-29 US disclosed
WO-2004022773-A1 FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS APPLERA CORPORATION (US) 2004-03-18 WO disclosed