Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682635 | 0.83 | — | — | |
| SCHEMBL9660243 | 0.78 | CYP3A4 (0.33) | THRB | |
| SCHEMBL5571941 | 0.78 | THRB (0.31) | THRB | |
| SCHEMBL27584519 | 0.74 | — | — | |
| SCHEMBL1792660 | 0.72 | — | — | |
| SCHEMBL3496904 | 0.70 | LMNA (0.35) | THRB | |
| SCHEMBL2867592 | 0.68 | CYP3A4 (0.36) | — | |
| SCHEMBL3012936 | 0.67 | — | — | |
| SCHEMBL3393450 | 0.67 | — | — | |
| SCHEMBL27589425 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230050846-A1 | TREATMENT OF HEPATIC AND CARDIOVASCULAR DISORDERS | UNIVERSITÉ PAUL SABATIER TOULOUSE III (FR) | 2023-02-16 | — | — | US | disclosed |
| WO-2021123300-A1 | TREATMENT OF HEPATIC AND CARDIOVASCULAR DISORDERS | LIFESEARCH (FR) | 2021-06-24 | — | — | WO | disclosed |
| US-20100112619-A1 | LIGAND-CONTAINING MICELLES AND USES THEREOF | GRAHAM RONALD J | 2010-05-06 | — | — | US | disclosed |
| EP-1537230-A4 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | APPLERA CORP (US) | 2008-06-18 | — | — | EP | disclosed |
| EP-1687635-A2 | LIGAND-CONTAINING MICELLES AND USES THEREOF | Applera Corporation (US) | 2006-08-09 | — | — | EP | disclosed |
| CN-1697880-A | Fluorogenic enzyme assay methods and compositions | APPLERA CORP (US) | 2005-11-16 | — | — | CN | disclosed |
| US-20050244891-A1 | Ligand-containing micelles and uses thereof | APPLERA CORPORATION (US) | 2005-11-03 | — | — | US | disclosed |
| WO-2005054495-A2 | LIGAND-CONTAINING MICELLES AND USES THEREOF | APPLERA CORPORATION (US) | 2005-06-16 | — | — | WO | disclosed |
| EP-1537230-A1 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | Applera Corporation (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20040146959-A1 | Fluorescent enzyme assay methods and compositions | APPLIED BIOSYSTEMS, LLC | 2004-07-29 | — | — | US | disclosed |
| WO-2004022773-A1 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | APPLERA CORPORATION (US) | 2004-03-18 | — | — | WO | disclosed |
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230050846-A1 | TREATMENT OF HEPATIC AND CARDIOVASCULAR DISORDERS | FABP1, FABP3, PCSK9 | MEN1 2676/4885CYP1A2 943/4885KMT2A 4386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.