Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770725 | 0.94 | CA1 (0.32) | CRBN | |
| SCHEMBL28125389 | 0.88 | — | — | |
| SCHEMBL525863 | 0.88 | — | — | |
| SCHEMBL11509552 | 0.82 | CRBN (0.38) | CRBN | |
| SCHEMBL7762508 | 0.78 | — | — | |
| SCHEMBL20183030 | 0.77 | — | — | |
| SCHEMBL20183036 | 0.77 | — | — | |
| SCHEMBL9621737 | 0.73 | GAA (0.37) | CRBN | |
| SCHEMBL7522014 | 0.72 | CA1 (0.35) | CRBN | |
| SCHEMBL28037791 | 0.72 | CHRM2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2537827-B1 | Process for preparing 4-amino-5-hexenoic acid from succinimide | TARGEON SAS (FR) | 2014-06-11 | — | — | EP | disclosed |
| EP-2537827-B1 | Process for preparing 4-amino-5-hexenoic acid from succinimide | TARGEON SAS (FR) | 2014-06-11 | — | — | EP | disclosed |
| US-20130165693-A1 | PROCESS FOR PREPARING 4-AMINO-5-HEXENOIC ACID AND INTERMEDIATES THEREOF | TARGEON (FR) | 2013-06-27 | — | — | US | disclosed |
| US-20130165693-A1 | PROCESS FOR PREPARING 4-AMINO-5-HEXENOIC ACID AND INTERMEDIATES THEREOF | TARGEON (FR) | 2013-06-27 | — | — | US | disclosed |
| US-20130165693-A1 | PROCESS FOR PREPARING 4-AMINO-5-HEXENOIC ACID AND INTERMEDIATES THEREOF | TARGEON (FR) | 2013-06-27 | — | — | US | disclosed |
| EP-2537827-A1 | Process for preparing 4-amino-5-hexenoic acid from succinimide | Targeon SAS (FR) | 2012-12-26 | — | — | EP | disclosed |
| EP-2537827-A1 | Process for preparing 4-amino-5-hexenoic acid from succinimide | Targeon SAS (FR) | 2012-12-26 | — | — | EP | disclosed |
| US-7659294-B2 | 2-(aryl)azacyclylmethyl carboxylates, sulfonates, phosphonates, phosphinates and heterocycles as S1P receptor agonists | MERCK & CO., INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20090042954-A1 | 2-(Aryl)Azacyclylmethyl Carboxylates, Sulfonates, Phosphonates, Phosphinates and Heterocycles as S1p Receptor Antagonists | MERCK SHARP & DOHME CORP. | 2009-02-12 | — | — | US | disclosed |
| EP-1804793-A2 | 2-(ARYL)AZACYCLYLMETHYL CARBOXYLATES, SULFONATES, PHOSPHONATES, PHOSPHINATES AND HETEROCYCLES AS S1P RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006047195-A2 | 2-(ARYL)AZACYCLYLMETHYL CARBOXYLATES, SULFONATES, PHOSPHONATES, PHOSPHINATES AND HETEROCYCLES AS S1P RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2006-05-04 | — | — | WO | disclosed |
| US-4025512-A | ANTIDEPRESSANTS | ABBOTT LABORATORIES (US) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165693-A1 | PROCESS FOR PREPARING 4-AMINO-5-HEXENOIC ACID AND INTERMEDIATES THEREOF | ALOX5, GRIK5, ALOX5AP | AKR1C3 498/4885AKR1C1 551/4885CRBN 1788/4885 |
| US-20090042954-A1 | 2-(Aryl)Azacyclylmethyl Carboxylates, Sulfonates, Phosphonates, Phosphinates and Heterocycles as S1p Receptor Antagonists | S1PR1, S1PR3, S1PR5 | AKR1C3 1319/4885AKR1C1 1606/4885CRBN 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.