Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.66 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.66 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.66 |
| ▸ | FAAH | O00519 | 1/20 | 0.66 |
| ▸ | ELANE | P08246 | 1/20 | 0.66 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.66 |
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | F12 | P00748 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | C1S | P09871 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537872 | 0.87 | PRSS1 (0.53) | PRSS1PRSS2PRSS3FAAHELANE | |
| Fluoride SCHEMBL8499766 | 0.86 | PRSS1 (0.52) | PRSS1PRSS2PRSS3FAAHELANE | |
| Hydrochloric Acid SCHEMBL1071756 | 0.86 | PRSS1 (0.52) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL11398465 | 0.85 | PRSS1 (0.59) | PRSS1PRSS2PRSS3FAAHELANE | |
| Hydrochloric Acid SCHEMBL3295507 | 0.83 | PRSS1 (0.57) | PRSS1PRSS2PRSS3FAAHELANE | |
| Benzamidine SCHEMBL11393583 | 0.81 | F2 (0.70) | PRSS1PRSS2PRSS3F2F10 | |
| Phenylmethylsulfonylfluoride SCHEMBL3965163 | 0.81 | PRSS1 (1.00) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethylsulfonylfluoride SCHEMBL24938 | 0.81 | PRSS1 (1.00) | PRSS1PRSS2PRSS3FAAHELANE | |
| Phenylmethanesulfonic Acid SCHEMBL7148383 | 0.81 | F2 (0.52) | PRSS1PRSS2PRSS3F2F10 | |
| Phenylmethylsulfonylfluoride SCHEMBL28507854 | 0.79 | PRSS1 (0.86) | PRSS1PRSS2PRSS3FAAHELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399631-B2 | Compositions and methods for purifying calreticulin | CALRETEX LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100145016-A1 | COMPOSITIONS AND METHODS FOR PURIFYING CALRETICULIN | CALRETEX, LLC (US) | 2010-06-10 | — | — | US | disclosed |