SCHEMBL537872

SCHEMBL537872

N=C(N)c1ccc(CS(=O)(=O)F)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 10/20 0.53
PRSS3 P35030 8/20 0.53
PRSS2 P07478 7/20 0.53
F10 P00742 1/20 0.53
LOXL2 Q9Y4K0 1/20 0.53
FAAH O00519 1/20 0.50
ELANE P08246 1/20 0.50
PRTN3 P24158 1/20 0.50
F2 P00734 7/20 0.49
PLG P00747 1/20 0.49
C1S P09871 1/20 0.49
ST14 Q9Y5Y6 4/20 0.46
TMPRSS6 Q8IU80 3/20 0.46
LMNA P02545 1/20 0.43
MASP2 O00187 1/20 0.43
PLAU P00749 1/20 0.43
THPO P40225 1/20 0.43
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL8499766 0.98 PRSS1 (0.52) PRSS1PRSS3PRSS2F10LOXL2
Hydrochloric Acid SCHEMBL1071756 0.98 PRSS1 (0.52) PRSS1PRSS3PRSS2F10LOXL2
Phenylmethylsulfonylfluoride SCHEMBL3497005 0.87 PRSS1 (0.66) PRSS1PRSS3PRSS2F10LOXL2
SCHEMBL15289189 0.82 PRSS1 (0.55) PRSS1PRSS3PRSS2F10LOXL2
SCHEMBL11547040 0.82 F10 (0.61) PRSS1PRSS3PRSS2F10LOXL2
SCHEMBL7531044 0.81 PRSS1 (0.50) PRSS1PRSS3PRSS2F10LOXL2
Ammonia Solution, Strong SCHEMBL11392652 0.81 F10 (0.59) PRSS1PRSS3PRSS2F10LOXL2
SCHEMBL9159309 0.81 PRSS1 (0.53) PRSS1PRSS3PRSS2F10LOXL2
Hydrochloric Acid SCHEMBL11396972 0.79 F10 (0.57) PRSS1PRSS3PRSS2F10LOXL2
Hydrochloric Acid SCHEMBL11394037 0.79 PRSS1 (0.52) PRSS1PRSS3PRSS2F10LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 827 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631514-A1 ORAL POLYPEPTIDE COMPOSITION AND USE THEREOF Hefei Tianhui Biotech Co., Ltd. (CN) 2025-10-15 EP claimed
US-20250281579-A1 Methods and Compositions for Oral Administration of Proteins ORAMED PHARMACEUTICALS INC (IL) 2025-09-11 US claimed
CN-119968205-A Oral polypeptide composition and application thereof 合肥天汇生物科技有限公司 2025-05-09 CN claimed
EP-4427588-A2 COMPOSITIONS FOR HEMOLYSIS AND COAGULATION REGULATION AND STABILIZATION OF EXTRACELLULAR VESICLES Streck LLC (US) 2024-09-11 EP claimed
CN-115119829-B Compositions for the modulation of haemolysis and coagulation of extracellular vesicles and stabilization 斯特雷克股份有限公司 2024-07-12 CN claimed
WO-2024120513-A1 ORAL POLYPEPTIDE COMPOSITION AND USE THEREOF 合肥天汇生物科技有限公司 2024-06-13 WO claimed
WO-2024085786-A1 MEDIUM AND DEVICE FOR COLLECTING, STORING AND TRANSPORTING Gra Olga Alekseevna (RU) 2024-04-25 WO claimed
EP-4356731-A1 MEDIUM AND DEVICE FOR COLLECTING, STORING AND TRANSPORTING BIOLOGICAL SAMPLES, AS WELL AS THEIR USE FOR THE STABILIZATION OF EXTRACELLULAR NUCLEIC ACIDS Gra, Olga Alekseevna (RU) 2024-04-24 EP claimed
CN-117398471-A Polypeptide composition, medicine, pharmaceutical composition and application thereof 合肥天汇生物科技有限公司 2024-01-16 CN claimed
CN-114848528-B Recombinant human lysozyme extract and preparation method and application thereof 广州恒雅生物化工有限公司 2023-07-14 CN claimed
EP-0641858-A1 SERUM CALCIUM DEPRESSING FACTOR Chugai Seiyaku Kabushiki Kaisha (JP) 1995-03-08 EP claimed
EP-0623146-A1 COMPOUNDS AND METHODS FOR INHIBITING $g(b)-PROTEIN FUNCTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-11-09 EP claimed
EP-0477274-B1 FACTOR Xa BASED ANTICOAGULANT COMPOSITIONS OKLAHOMA MED RES FOUND (US) 1994-02-23 EP claimed
WO-1993015112-A2 COMPOUNDS AND METHODS FOR INHIBITING β-PROTEIN FUNCTION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1993-08-05 WO claimed
US-5120537-A FACTOR XA BASED ANTICOAGULANT COMPOSITIONS OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 1992-06-09 US claimed
EP-0477274-A1 FACTOR Xa BASED ANTICOAGULANT COMPOSITIONS. OKLAHOMA MED RES FOUND (US) 1992-04-01 EP claimed
US-5053333-A Specific for pared basic amino acid residues M & D RESEARCH CO., LTD. (JP) 1991-10-01 US claimed
WO-1990015619-A1 FACTOR Xa BASED ANTICOAGULANT COMPOSITIONS OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) 1990-12-27 WO claimed
EP-0336056-A1 Protease M & D RESEARCH CO., LTD. (JP) 1989-10-11 EP claimed
US-4303592-A SERINE PROTEASE INHIBITORS CENTER FOR BLOOD RESEARCH, INC. (US) 1981-12-01 US claimed