SCHEMBL3497074

SCHEMBL3497074

CCCCCNC(=O)C1C2CCC(O2)C1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
TFPI2 P48307 2/20 0.52
KDM4E B2RXH2 1/20 0.52
GMNN O75496 1/20 0.52
PMP22 Q01453 1/20 0.52
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
NFKB1 P19838 1/20 0.52
THPO P40225 1/20 0.52
ALDH1A1 P00352 1/20 0.51
MAPK1 P28482 1/20 0.51
PPM1B O75688 3/20 0.50
PTPN1 P18031 3/20 0.50
PPP1CC P36873 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
POLB P06746 1/20 0.49
NAAA Q02083 1/20 0.49
PPP1CA P62136 1/20 0.48
PRCP P42785 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13311753 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL13311750 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL3495237 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL3875657 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL13311513 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL3493746 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL3494796 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL3495890 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL3495818 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22
SCHEMBL3495465 0.98 NAAA (0.51) LMNATFPI2KDM4EGMNNPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2086534-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS Genetic Technologies Limited (AU) 2009-08-12 EP claimed
WO-2008058342-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2008-05-22 WO claimed
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2010-06-03 US disclosed
EP-2086534-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS Genetic Technologies Limited (AU) 2009-08-12 EP disclosed
WO-2008058342-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2008-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS PPP1R10, TASP1, PPP5C LMNA 4332/4885TFPI2 1086/4885KDM4E 1897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.