Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.72 |
| ▸ | ECE1 | P42892 | 12/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051627 | 1.00 | ACE (0.72) | ACEECE1ALOX15 | |
| SCHEMBL29400177 | 0.95 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL2488765 | 0.95 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL1228369 | 0.95 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL9235801 | 0.95 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL9235805 | 0.95 | ACE (0.78) | ACEECE1ALOX15 | |
| SCHEMBL29749345 | 0.94 | ACE (0.63) | ACEECE1 | |
| SCHEMBL30051087 | 0.93 | ACE (0.75) | ACEECE1ALOX15 | |
| SCHEMBL31259939 | 0.92 | ACE (0.71) | ACEECE1ALOX15 | |
| SCHEMBL10753134 | 0.92 | ACE (0.71) | ACEECE1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10874678-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20190262364-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2019-08-29 | — | — | US | disclosed |
| US-8536133-B2 | Selective high-affinity polydentate ligands and methods of making such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC. (US) | 2013-09-17 | — | — | US | disclosed |
| US-20100184702-A1 | Selective High-Affinity Polydentate Ligands and Methods of Making Such | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184702-A1 | Selective High-Affinity Polydentate Ligands and Methods of Making Such | CD44, FCGR3B, FCGR2A | ACE 4417/4885ECE1 2236/4885ALOX15 4845/4885 |
| US-20190262364-A1 | SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH | CD44, FCGR3B, FCGR2A | ACE 4417/4885ECE1 2236/4885ALOX15 4845/4885 |
| US-10874678-B2 | Selective high-affinity polydentate ligands and methods of making such | CD44, FCGR3B, FCGR2A | ACE 4417/4885ECE1 2236/4885ALOX15 4845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.