Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976793 | 0.83 | EPHX1 (0.34) | MEN1KMT2AL3MBTL1HTTLMNA | |
| SCHEMBL3502527 | 0.77 | MEN1 (0.46) | MEN1KMT2AL3MBTL1HTTLMNA | |
| SCHEMBL2968659 | 0.74 | L3MBTL1 (0.43) | MEN1KMT2AL3MBTL1HTTLMNA | |
| SCHEMBL13203992 | 0.73 | IDO1 (0.51) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL2656387 | 0.73 | CYP1A2 (0.45) | L3MBTL1LMNAALDH1A1EPHX1PPARG | |
| SCHEMBL1039681 | 0.72 | CYP1A2 (0.40) | L3MBTL1LMNAEPHX1TSHRCYP1A2 | |
| SCHEMBL2668750 | 0.72 | L3MBTL1 (0.37) | L3MBTL1LMNAALDH1A1EPHX1PPARG | |
| SCHEMBL1527188 | 0.70 | MEN1 (0.49) | MEN1KMT2AL3MBTL1HTTLMNA | |
| SCHEMBL1417470 | 0.70 | CPA1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1EPHX1 | |
| SCHEMBL8773482 | 0.69 | MEN1 (0.69) | MEN1KMT2AL3MBTL1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410087-B2 | Indole compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-04-02 | — | — | US | disclosed |
| US-20100144702-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144702-A1 | INDOLE COMPOUND | GCKR, GPR119, SLC5A1 | MEN1 2138/4885KMT2A 507/4885L3MBTL1 2173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.