Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.60 |
| ▸ | TPMT | P51580 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4371939 | 0.97 | PARP1 (0.58) | PARP1TPMTTSHRHCAR1ADRA1D | |
| SCHEMBL14060424 | 0.95 | PARP1 (0.56) | PARP1TPMTTSHRHCAR1ADRA1D | |
| SCHEMBL5048829 | 0.94 | PARP1 (0.60) | PARP1TPMTTSHRHCAR1ADRA1D | |
| SCHEMBL28037673 | 0.87 | PARP1 (0.48) | PARP1TPMTTSHRHCAR1ADRA1D | |
| SCHEMBL4339312 | 0.85 | HCAR1 (0.65) | PARP1TPMTTSHRHCAR1ADRA1D | |
| SCHEMBL16952186 | 0.84 | PARP1 (0.50) | PARP1TPMTTSHRHCAR1ADRA1D | |
| SCHEMBL1363329 | 0.84 | PARP1 (0.50) | PARP1TPMTTSHRHCAR1ADRA1D | |
| SCHEMBL9631667 | 0.84 | PARP1 (0.50) | PARP1TPMTHCAR1ADRA1DCYP3A4 | |
| SCHEMBL22383502 | 0.84 | PARP1 (0.50) | PARP1TPMTHCAR1ADRA1DMAP4K4 | |
| SCHEMBL30463182 | 0.84 | PARP1 (0.50) | PARP1TPMTHCAR1ADRA1DCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119875232-A | Flame-retardant cable and preparation method thereof | 佰汇电缆有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-113372290-A | Synthetic method of drug Tafamidis | 遵义医科大学 | 2021-09-10 | — | — | CN | claimed |
| CN-109232649-B | Tetrazole urease inhibitor type feed additive and preparation method thereof | 北京绿摇饲料科技有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-109232646-B | Triazole urease inhibitor type feed additive and preparation method thereof | 赣州澳德饲料科技有限公司 | 2020-08-21 | — | — | CN | claimed |
| CN-110642741-A | Functionalized benzamide derivatives as antiviral agents against HBV infection | 巴鲁克斯布隆伯格研究所 | 2020-01-03 | — | — | CN | claimed |
| CN-104918612-B | Functionalized benzamide derivatives as antiviral agents against HBV infection | 巴鲁克斯布隆伯格研究所 | 2019-10-25 | — | — | CN | claimed |
| CN-109232646-A | A kind of triazole urease inhibitor type feed addictive and preparation method thereof | 河南湾流生物科技有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-109232649-A | A kind of tetrazole urease inhibitor type feed addictive and preparation method thereof | 河南湾流生物科技有限公司 | 2019-01-18 | — | — | CN | claimed |
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | claimed |
| CN-105542584-A | Thermal-inductive fluorocarbon function coating containing azobenzene/carbon-hybrid material and preparation method of thermal-inductive fluorocarbon function coating | UNIV TIANJIN | 2016-05-04 | — | — | CN | claimed |
| WO-2003066579-A2 | NOVEL BICYCLIC HYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | AXYS PHARMACEUTICALS (US) | 2003-08-14 | — | — | WO | claimed |
| WO-2003059899-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL FORMULATIONS CONTAINING THEM AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-07-24 | — | — | WO | claimed |
| US-20030069259-A1 | Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents | AVENTISUB LLC | 2003-04-10 | — | — | US | claimed |
| WO-2002044126-A2 | BISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIRUS | GUILFORD PHARMACEUTICALS INC. (US) | 2002-06-06 | — | — | WO | claimed |
| WO-2002042303-A2 | ACYL AND SULFONYL DERIVATIVES OF 6,9-DISUBSTITUTED 2-(TRANS-1,4-DIAMINOCYCLOHEXYL)-PURINES AND THEIR USE AS ANTIPROLIFERATIVE AGENTS | AVENTIS PHARMACEUTICALS INC. (US) | 2002-05-30 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| CN-1246112-A | Improved process for preparation of halo-4-phenoxyquinolines | DOW AGROSCIENCES LLC (US) | 2000-03-01 | — | — | CN | claimed |
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069259-A1 | Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents | BAD, BAX, MCL1 | PARP1 208/4885TPMT 321/4885TSHR 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.