SCHEMBL349824

SCHEMBL349824

CC1(C)c2cc(N)ccc2-c2ccc(N)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.44
ALDH1A1 P00352 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
LMNA P02545 4/20 0.39
NPC1 O15118 3/20 0.39
MAPT P10636 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
CHEK1 O14757 1/20 0.38
PRKD3 O94806 1/20 0.38
MAP4K4 O95819 1/20 0.38
RET P07949 1/20 0.38
MET P08581 1/20 0.38
PDGFRA P16234 1/20 0.38
FLT1 P17948 1/20 0.38
LTK P29376 1/20 0.38
PRKX P51817 1/20 0.38
NEK2 P51955 1/20 0.38
JAK3 P52333 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29479852 1.00 PDK2 (0.44) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL30340812 1.00 PDK2 (0.44) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL14073332 0.98 PDK2 (0.43) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL23546585 0.93 PDK2 (0.42) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL344471 0.89 PDK2 (0.54) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL29362446 0.89 PDK2 (0.54) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL29361678 0.89 PDK2 (0.54) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL19074899 0.89 SMN1; SMN2 (0.41) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL13907822 0.88 PDK2 (0.53) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA
SCHEMBL14305890 0.88 MAPT (0.45) PDK2ALDH1A1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344646-A Preparation method of shape memory fluorine-containing block polyimide aerogel with flexibility 江南大学 2024-07-16 CN claimed
CN-118221936-A High-performance preparation method and application of polyimide 中国科学院化学研究所 2024-06-21 CN claimed
CN-118027402-A Corona-resistant polyimide, preparation method thereof and insulated wire 深圳市摩码克来沃化学科技有限公司 2024-05-14 CN claimed
CN-117186399-A Polymer, polymer film and preparation method thereof 华为技术有限公司 2023-12-08 CN claimed
CN-116536034-A Preparation method of polyimide graphitized film 东营欣邦电子科技有限公司 2023-08-04 CN claimed
CN-116239988-A Adhesive, and preparation method and application thereof 安徽壹石通材料科学研究院有限公司 2023-06-09 CN claimed
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 EP claimed
CN-101812304-B Liquid crystal aligning agent, liquid crystal display device and fabricating method thereof JSR CO LTD 2014-03-19 CN claimed
JP-11035532-A None JP disclosed
CN-118344646-A Preparation method of shape memory fluorine-containing block polyimide aerogel with flexibility 江南大学 2024-07-16 CN disclosed
CN-118307779-A Preparation method and application of high-performance polyimide 中国科学院化学研究所 2024-07-09 CN disclosed
CN-118221936-A High-performance preparation method and application of polyimide 中国科学院化学研究所 2024-06-21 CN disclosed
CN-118027402-A Corona-resistant polyimide, preparation method thereof and insulated wire 深圳市摩码克来沃化学科技有限公司 2024-05-14 CN disclosed
EP-0879868-B1 Organic compound and electroluminescent device using the same CANON KK (JP) 2002-04-03 EP disclosed
JP-2000016973-A NEW TRIARYLAMINE COMPOUND AND LIGHT EMISSION ELEMENT USING THE SAME CANON INC 2000-01-18 JP disclosed
EP-0953624-A1 Triarylamine compound and luminescent device CANON KABUSHIKI KAISHA (JP) 1999-11-03 EP disclosed
JP-H1135532-A ORGANIC COMPOUND AND LIGHT EMISSION DEVICE USING THE SAME CANON INC 1999-02-09 JP disclosed
EP-0879868-A2 Organic compound and electroluminescent device using the same CANON KABUSHIKI KAISHA (JP) 1998-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 PDK2 646/4885ALDH1A1 1659/4885RAB9A 1963/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 PDK2 1221/4885ALDH1A1 1627/4885RAB9A 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.