SCHEMBL349833

SCHEMBL349833

O=[C]CCSSc1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.53
EHMT1 Q9H9B1 1/20 0.53
APOBEC3G Q9HC16 1/20 0.53
ALDH1A1 P00352 6/20 0.42
KMT2A Q03164 5/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 3/20 0.36
PKM P14618 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
NPC1 O15118 5/20 0.36
RAB9A P51151 5/20 0.36
HPGD P15428 4/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
USP2 O75604 1/20 0.36
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11833495 0.83 EHMT2 (0.70) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL1495026 0.83 EHMT2 (0.53) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL14115866 0.83 EHMT2 (0.53) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL5580505 0.82 ALDH1A1 (0.57) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL11822538 0.80 EHMT2 (0.64) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL14524400 0.80 EHMT2 (0.64) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL11830911 0.80 EHMT2 (0.64) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL17610651 0.79 EHMT2 (0.48) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL5053893 0.79 EHMT2 (0.48) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL15667399 0.79 EHMT2 (0.48) EHMT2EHMT1APOBEC3GALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478049-B1 A POLYMER SUPPORT UNIV CAPE TOWN (ZA) 2015-02-25 EP claimed
CN-101421323-B Loaded latex optical molecular imaging probes CARESTREAM HEALTH INC 2013-03-13 CN claimed
CN-101421323-A Loaded latex optical molecular imaging probes CARESTREAM HEALTH INC (US) 2009-04-29 CN claimed
EP-1605979-B1 CONJUGATES FOR MEDICAL IMAGING COMPRISING CARRIER, TARGETING MOIETY AND A CONTRAST AGENT UPPERTON LTD (GB) 2008-10-22 EP claimed
WO-2006109311-A2 ENZYME-CHANNELING BASED ELECTROCHEMICAL BIOSENSORS RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2006-10-19 WO claimed
WO-2024145445-A1 METHODS OF CAPTURING TARGET ANALYTES 10X GENOMICS, INC. (US) 2024-07-04 WO disclosed
WO-2024138016-A1 METHODS AND MATERIALS FOR PERFORMING ELECTROCHEMICAL ASSAYS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2024-06-27 WO disclosed
CN-118217402-A Combination therapy for C3 inhibition 阿佩利斯制药有限公司 2024-06-21 CN disclosed
CN-118103709-A Space coding for suspension mass spectrometry flow cytometry 标准生物工具加拿大公司 2024-05-28 CN disclosed
WO-2024081739-A2 COVALENT COMPOUNDS AND USES THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2024-04-18 WO disclosed
US-20240115655-A1 DOSING REGIMENS AND RELATED COMPOSITIONS AND METHODS SIXTH STREET LENDING PARTNERS 2024-04-11 US disclosed
EP-4349363-A2 DOSING REGIMENS Apellis Pharmaceuticals, Inc. (US) 2024-04-10 EP disclosed
US-4529712-A Amino reactive end of a heterobifunctional crosslinking reagent connects to thiol reactive compound RESEARCH CORPORATION (US) 1985-07-16 US disclosed
EP-0146050-A2 Site selective plasminogen activator and method of making and using same Callewaert, Denis M. (US) 1985-06-26 EP disclosed
EP-0124221-A1 Method of detecting a polynucleotide sequence and labelled polynucleotides useful therein Malcolm, Alan David Blair (GB) 1984-11-07 EP disclosed
WO-1984003520-A1 METHOD OF DETECTING A POLYNUCLEOTIDE SEQUENCE AND LABELLED POLYNUCLEOTIDES USEFUL THEREIN BLAIR MALCOLM A D 1984-09-13 WO disclosed
EP-0112720-A2 Conjugate having cytotoxicity and process for the preparation thereof TEIJIN LIMITED (JP) 1984-07-04 EP disclosed
US-4429008-A AGGLUTINATION ASSAYS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1984-01-31 US disclosed
EP-0097691-A1 THIOL REACTIVE LIPOSOMES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1984-01-11 EP disclosed
WO-1983002069-A1 THIOL REACTIVE LIPOSOMES UNIV CALIFORNIA (US) 1983-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115655-A1 DOSING REGIMENS AND RELATED COMPOSITIONS AND METHODS C1QBP, C3AR1, C9 EHMT2 4611/4885EHMT1 4378/4885APOBEC3G 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.