Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 5/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | ALAD | P13716 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498018 | 0.87 | BCL2L1 (0.53) | RPA1BCL2L1ALADGPR35CCNC | |
| SCHEMBL15697540 | 0.87 | BCL2L1 (0.66) | BCL2L1GPR35POLBRAB9AHDAC1 | |
| SCHEMBL156320 | 0.86 | BCL2L1 (0.59) | RPA1BCL2L1GPR35PRSS12CCNC | |
| SCHEMBL3499141 | 0.85 | HDAC1 (0.51) | RPA1ALADCCNCCDK8KDM4E | |
| SCHEMBL17173215 | 0.84 | HDAC1 (0.54) | RPA1BCL2L1GPR35TBXAS1KDM4E | |
| SCHEMBL23480398 | 0.79 | BCL2L1 (0.64) | RPA1BCL2L1GPR35TBXAS1NOTUM | |
| SCHEMBL3500539 | 0.79 | MAPT (0.50) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15697564 | 0.77 | AKR1C2 (0.49) | BCL2L1GPR35HDAC6 | |
| SCHEMBL29742302 | 0.76 | BCL2L1 (0.59) | BCL2L1GPR35CCNCCDK8TBXAS1 | |
| SCHEMBL740202 | 0.76 | BCL2L1 (0.59) | BCL2L1GPR35CCNCCDK8TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | RPA1 2894/4885BCL2L1 2669/4885ALAD 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.