Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | EPOR | P19235 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | BCL2 | P10415 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498438 | 1.00 | AR (0.57) | ARLTA4HMEN1KMT2AEPOR | |
| SCHEMBL3498101 | 0.84 | AR (0.60) | ARLTA4HMEN1KMT2ABCL2 | |
| SCHEMBL3498103 | 0.84 | AR (0.60) | ARLTA4HMEN1KMT2ABCL2 | |
| SCHEMBL32668280 | 0.80 | MEN1 (0.48) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL21995328 | 0.78 | MEN1 (0.49) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL21995330 | 0.78 | MEN1 (0.49) | MEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL28624157 | 0.78 | MEN1 (0.48) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL18380161 | 0.75 | MEN1 (0.41) | ARMEN1KMT2AEPOR | |
| SCHEMBL18379930 | 0.75 | MEN1 (0.49) | MEN1KMT2AEPOR | |
| SCHEMBL16552347 | 0.74 | MAOB (0.70) | LTA4HEPORMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | AR 115/4885LTA4H 1788/4885MEN1 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.