Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369368 | 0.85 | PNP (0.37) | CYP2E1CYP2A6CYP2B6CDK8ALDH1A1 | |
| SCHEMBL17622 | 0.82 | CXCR2 (0.42) | KDM4EHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8588873 | 0.81 | CXCR2 (0.41) | KDM4EHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL17279789 | 0.78 | SMN1; SMN2 (0.42) | KDM4EHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7010798 | 0.76 | TAAR1 (0.41) | CYP2E1CYP2A6CYP2B6CDK8PDGFRB | |
| SCHEMBL7487640 | 0.76 | NPC1 (0.43) | CYP17A1CYP11B1CYP11B2KDM4EHSD17B10 | |
| SCHEMBL14059820 | 0.75 | CYP2A6 (0.50) | CYP2E1CYP2A6CYP2B6CDK8PDGFRB | |
| SCHEMBL7100910 | 0.73 | GSK3B (0.41) | CYP2E1CYP2A6CYP2B6CDK8CYP17A1 | |
| SCHEMBL8973626 | 0.73 | GABRA1 (0.55) | KDM4EHSD17B10ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28783020 | 0.73 | TAAR1 (0.47) | CYP2A6CDK8KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168443-A1 | Ethoid-Containing Compounds, Methods for Preparing Ethoid-Containing Compounds, and Methods of Use | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168443-A1 | Ethoid-Containing Compounds, Methods for Preparing Ethoid-Containing Compounds, and Methods of Use | PARG, POLH, PHOSPHO1 | CYP2E1 1058/4885CYP2A6 1457/4885CYP2B6 1971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.