Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.97 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.97 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.53 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL137600 | 0.98 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| Histidine SCHEMBL388560 | 0.98 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| Histidine SCHEMBL3260 | 0.98 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| Histidine SCHEMBL30852263 | 0.98 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| Histidine SCHEMBL19974306 | 0.98 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| Histidine SCHEMBL28071764 | 0.98 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| D-Histidine SCHEMBL288043 | 0.98 | CYP3A4 (1.00) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| Histidine SCHEMBL25362582 | 0.97 | CYP3A4 (0.97) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| Histidine SCHEMBL25357958 | 0.97 | CYP3A4 (0.97) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 | |
| Histidine SCHEMBL25267810 | 0.97 | CYP3A4 (0.97) | CYP3A4SLC7A5CPB2ALDH1A1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109965104-A | A kind of composition and its preparation method and application containing Sodium Hyaluronate | 华熙生物科技股份有限公司 | 2019-07-05 | — | — | CN | claimed |
| US-20230145406-A1 | DIVALENT METAL-CONTAINING BIOMATERIALS AND METHODS OF USE | UNIVERSITY OF OREGON (US) | 2023-05-11 | — | — | US | disclosed |
| CN-113277954-B | Amino acid metal chelate micro-nano powder and preparation method thereof | 英德市匠心新材料股份有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-111662342-B | Preparation method of tannin-histidine metal complex | 太原理工大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-113277954-A | Amino acid metal chelate micro-nano powder and preparation method thereof | 英德市匠心新材料股份有限公司 | 2021-08-20 | — | — | CN | disclosed |
| WO-2021011540-A1 | ORAL IRON COMPOSITIONS AND APPLICATION FOR BABY PIGS | NOVUS INTERNATIONAL INC. (US) | 2021-01-21 | — | — | WO | disclosed |
| CN-106730049-B | Biocompatible internal stent material | 深圳汉诺医疗科技有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-110204492-A | A kind of preparation method of novel amino chelated iron crystal | 南京理工大学 | 2019-09-06 | — | — | CN | disclosed |
| CN-109965104-A | A kind of composition and its preparation method and application containing Sodium Hyaluronate | 华熙生物科技股份有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-102712911-B | Comprise the allelic Brassica plants of sudden change FAD3 | BAYER CROPSCIENCE N.V. (BE) | 2016-01-13 | — | — | CN | disclosed |
| CN-102712911-A | Brassica plants comprising mutant FAD3 alleles | BAYER BIOSCIENCE NV | 2012-10-03 | — | — | CN | disclosed |
| US-20100172862-A1 | STABLE ANTIBODY COMPOSITIONS AND METHODS OF STABILIZING SAME | ABBOTT LABORATORIES (US) | 2010-07-08 | — | — | US | disclosed |
| US-20080090297-A1 | Methods for determining the metal bioavailability of metal sources | NOVUS INTERNATIONAL INC. (US) | 2008-04-17 | — | — | US | disclosed |
| US-20040137483-A1 | Lipoxygenase proteins and nucleic acids | BRASH ALAN R (US) | 2004-07-15 | — | — | US | disclosed |
| US-6649355-B2 | Lipoxygenase proteins and nucleic acids | VANDERBILT UNIVERSITY | 2003-11-18 | — | — | US | disclosed |
| US-20010046672-A1 | Lipoxygenase proteins and nucleic acids | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2001-11-29 | — | — | US | disclosed |
| US-6204037-B1 | NUCLEOTIDE SEQUENCES THAT CODE ENZYMATIC POLYPEPTIDE; FOR MONITORING THE METABOLISM OF ARACHIDONIC ACID IN PREFERENTIAL CELLS; AND TREATMENT OF INFLAMMATION AND INJURIES | VANDERBILT UNIVERSITY | 2001-03-20 | — | — | US | disclosed |