Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498794 | 0.85 | ACACB (0.64) | ACACBACACA | |
| SCHEMBL3498870 | 0.84 | ACACB (0.74) | ACACBACACA | |
| SCHEMBL3497657 | 0.83 | ACACB (0.69) | ACACBACACA | |
| SCHEMBL4723439 | 0.83 | ACACB (0.84) | ACACBACACA | |
| SCHEMBL3497028 | 0.83 | ACACB (0.70) | ACACBACACA | |
| SCHEMBL3496726 | 0.81 | ACACB (0.83) | ACACBACACA | |
| SCHEMBL13312524 | 0.81 | ACACB (0.78) | ACACBACACA | |
| SCHEMBL3497941 | 0.81 | ACACB (0.87) | ACACBACACA | |
| SCHEMBL3496708 | 0.80 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL3497404 | 0.79 | ACACB (0.68) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160255-A1 | SPIRO-CYCLIC COMPOUND | ACACA, CPT1B, PC | ACACB 6/4885ACACA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.